Results 31 to 40 of about 50,311 (298)

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic
Kristina Svennerholm, Pouria Rodsand, Urban Hellman, Marie Lundholm, Anders Waldenström, Björn Biber, Gunnar Ronquist, Michael Haney   +7 more
doaj   +1 more source

The method of distant preconditioning and results of its application in renal transplantation from the living family donor

Клінічна хірургія, 2021
Objective. Elaboration of method for the intraoperative ischemic-reperfusion trauma softening - distant ischemic preconditioning and investigation of results of its introduction into clinical practice. Materials and methods.
M. І. Kyrychenko, A. V. Bilyayev, N. G. Davydenko, A. O. Bychkova, O. V. Storozhuk   +4 more
doaj   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ, Hollmann, Markus W, Konkel, Moritz, Oei, Gezina TML, Patel, Hemal H, Preckel, Benedikt, Smit, Kirsten F, Weber, Nina C   +7 more
core   +1 more source

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. [PDF]

, 2019
Prenatal stem cell-based regenerative therapies have progressed substantially and have been demonstrated as effective treatment options for fetal diseases that were previously deemed untreatable. Due to immunoregulatory properties, self-renewal capacity,
Farmer, Diana L, Guo, Fuzheng, Hao, Dake, He, Chuanchao, Lankford, Lee, Ma, Bowen, Reynaga, Lizette, Wang, Aijun   +7 more
core   +1 more source

Novel role for the innate immune receptor toll-like receptor 4 (TLR4) in the regulation of the wnt signaling pathway and photoreceptor apoptosis [PDF]

, 2012
Recent evidence has implicated innate immunity in regulating neuronal survival in the brain during stroke and other neurodegenerations. Photoreceptors are specialized light-detecting neurons in the retina that are essential for vision.
A Poltorak, A Wenzel, Abigail S. Hackam, AK Silva, AL Kindzelskii, Amit K. Patel, AO Edwards, AS Hackam, B Marsh, BJ Marsh, BJ Marsh, C Bowes, C Liu, C Niehrs, C Zhang, Chhinder P. Sodhi, CP Sodhi, CY Logan, D Jiang, David J. Hackam, DJ Kaczorowski, E Cario, E Chaum, E Okun, F Hua, F Limana, G Faraco, G Tezel, GA Limb, GM Seigel, GR Barile, GS Hageman, GT Higgins, H Yi, H Yi, HL Rosenzweig, HL Rosenzweig, HP Scholl, Hyun Yi, IA El-Ghrably, J Merenmies, J Qiu, J Watson, JK Shen, JR Caso, K Hoshino, K Kaarniranta, K Miyake, K Takeda, KP Mollen, L Barandon, L Minghetti, M Mizukami, MA Fragoso, Mauricio Martins Rodrigues, MD Gordon, MK Ko, MT Lotze, N Arimura, P Matzinger, PJ Franco, PY Leung, Q Xing, R Gauthier, R Gorina, R Kacimi, R Seitz, R Shechter, RM Vabulas, RR Caspi, RT Moon, S Lehnardt, S Lin, S Tell, S Walter, S Zareparsi, SC Gribar, SC Tang, SC Tang, SR Coats, T Ha, T Harada, T Harada, T Nakazawa, U Kilic, V Bocchini, V Fontaine, Y de Kozak, Y Xin, Z Tu   +89 more
core   +9 more sources

NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia

Neurobiology of Disease, 2012
Substantial evidence has established that a short sub-lethal brain ischemia applied before a prolonged harmful ischemic episode confers ischemic neuroprotection, a phenomenon named ischemic preconditioning.
Giuseppe Pignataro, Francesca Boscia, Elga Esposito, Rossana Sirabella, Ornella Cuomo, Antonio Vinciguerra, Gianfranco Di Renzo, Lucio Annunziato   +7 more
doaj   +1 more source

Safety and Feasibility of Remote Limb Ischemic Preconditioning in Patients with Unilateral Middle Cerebral Artery Stenosis and Healthy Volunteers

Cell Transplantation, 2015
Previous studies have indicated a neuroprotective effect of remote limb ischemic preconditioning. The aim of the present study was to assess whether upper arm ischemic preconditioning is feasible and safe in patients with unilateral middle cerebral ...
Sijie Li, Chun Ma, Guo Shao, Fatema Esmail, Yang Hua, Lingyun Jia, Jian Qin, Changhong Ren, Yumin Luo, Yuchun Ding, Cesario V. Borlongan, Xunming Ji   +11 more
doaj   +1 more source

Neuroprotective effects of ischemic preconditioning on hippocampal CA1 pyramidal neurons through maintaining calbindin D28k immunoreactivity following subsequent transient cerebral ischemia

Neural Regeneration Research, 2017
Ischemic preconditioning elicited by a non-fatal brief occlusion of blood flow has been applied for an experimental therapeutic strategy against a subsequent fatal ischemic insult.
In Hye Kim, Yong Hwan Jeon, Tae-Kyeong Lee, Jeong Hwi Cho, Jae-Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Bich-Na Shin, Yang Hee Kim, Seongkweon Hong, Bing Chun Yan, Moo-Ho Won, Yun Lyul Lee   +12 more
doaj   +1 more source

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]

, 2006
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A, Dimmeler, S, Heeschen, C, Sasaki, K, Urbich, C, Zeiher, AM   +5 more
core   +1 more source

Preconditioning in cardiac anesthesia…… where are we?

Annals of Cardiac Anaesthesia, 2019
Preconditioning, a milestone concept in the cardiovascular sciences introduced 32 years back by Murry. This concept opened a new era in the field of organ protection.
Ajita Suhrid Annachhatre, Suhrid R Annachhatre   +1 more
doaj   +1 more source