Results 31 to 40 of about 262,486 (214)

Regulation of gap junction function; the role of nitric oxide. [PDF]

, 2013
Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Kovács Mária, Miskolczi Gottfried, Végh, Ágnes, Gönczi, Márton, Végh Ágnes, Gottfried Miskolczi, Miskolczi eGottfried, Miskolczi, Gottfried, Kovács, Mária, Gönczi eMárton, Kovács eMária, Gönczi Márton, Ágnes Végh, Mária Kovács, Ágnes eVégh, Márton Gönczi   +15 more
core   +1 more source

Preconditioning as a method of neuroprotection in a model of brain infarct

Анналы клинической и экспериментальной неврологии, 2017
Preconditioning of ischemic and hypoxic type was investigated as a method of protecting brain against acute ischemic injury. The preconditioning methods were applied to experimental rats 24 h before the time when local brain infarct was done by middle ...
R. M. Khudoerkov, N. S. Samojlenkova, S. A. Gavrilova, Yu. A. Pirogov, V. B. Koshelev   +4 more
doaj   +1 more source

Sevoflurane preconditioning induces tolerance to brain ischemia partially via inhibiting thioredoxin-1 nitration

BMC Anesthesiology, 2018
Background Sevoflurane preconditioning induces brain ischemic tolerance, but the mechanism remains poorly elucidated. Nitration is an important form of post-translational modification in pathological signaling.
Shiquan Wang, Yuheng Li, Jinlong Wei, Pei Li, Qianzi Yang   +4 more
doaj   +1 more source

EFEITOS DO PRÉ-CONDICIONAMENTO HEPÁTICO EM RATOS CIRRÓTICOS, SUBMETIDOS À ISQUEMIA E REPERFUSÃO HEPÁTICA RESULTADOS PRELIMINARES PRECONDITIONING WITH ISCHEMIC-REPERFUSION FOR PROTECTION FROM ISCHEMIC INJURY IN RAT LIVER CIRRHOSIS PRELIMINARY RESULT

Acta Cirúrgica Brasileira, 2001
Baseando-se nos efeitos estimuladores do metabolismo energético pelo pré-condicionamento isquêmico (PCI) no tecido hepático, estudou-se dois grupos de ratos cirróticos submetidos a isquemia de 20 min e reperfusão de 120 min, após o PCI ou não ...
E.G. Pacheco, F.S. Ramalho, L.N.Z. Ramalho, S. Zucoloto, O. Castro e Silva Jr., A.F. Oliveira   +5 more
doaj   +1 more source

Signalling pathways involved in TNFα-induced cytoprotection : role of reactive oxygen species [PDF]

, 2005
Includes bibliographical references (leaves 73-89).Tumour necrosis factor alpha (TNFa) is a pleiotropic cytokine which has both beneficial and deleterious effects.
Lacerda, Lydia
core   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Remote preconditioning by aortic constriction: affords cardioprotection as classical or other remote ischemic preconditioning? Role of iNOS [PDF]

, 2011
Dose remote preconditioning by aortic constriction (RPAC) affords cardioprotection similar to classical or other remote ischemic preconditioning stimulus?
Ashok Sharma, Akash Sharma, Ashish Sharma, Ashish Tiwari, Divya Sharma, Arshee Munajjam, Kunal Kishore, Rita Kumari, Shyam Agarwal, B.P. Srinivasan, Bhawna Vaishnav, Richa Sharma   +11 more
core  

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Effect of Staged Preconditioning on BiochemicalMarkers in the Patients Undergoing Coronary Artery Bypass Grafting [PDF]

The present study has investigated the effectiveness of staged-preconditioning, in both remote and target organs. After IP the myocardial release of the biochemicalmarkers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB ...
حسینیان, عدالت, دوستکامی, حسین, جعفری, ناصر, باباپور, بهزاد, محمدزاده, علیرضا, حسن پور, محمد   +5 more
core   +1 more source