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Plastic and Reconstructive Surgery, 2006
The restoration of blood flow to ischemic tissues causes additional damage, which is termed reperfusion injury. All tissues are susceptible to reperfusion injury, but this susceptibility varies between tissues. Reperfusion has wide clinical relevance. It influences the outcome of patients after myocardial infarction, stroke, organ transplantation, and ...
Alizan A, Khalil +2 more
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The restoration of blood flow to ischemic tissues causes additional damage, which is termed reperfusion injury. All tissues are susceptible to reperfusion injury, but this susceptibility varies between tissues. Reperfusion has wide clinical relevance. It influences the outcome of patients after myocardial infarction, stroke, organ transplantation, and ...
Alizan A, Khalil +2 more
openaire +2 more sources
Surgical Clinics of North America, 1992
In conclusion, a large body of evidence demonstrates that reperfusion of ischemic intestine results in significant microvascular and parenchymal cell injury. Reperfusion injury appears to be mediated by both reactive oxygen metabolites and activated polymorphonuclear leukocytes.
B J, Zimmerman, D N, Granger
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In conclusion, a large body of evidence demonstrates that reperfusion of ischemic intestine results in significant microvascular and parenchymal cell injury. Reperfusion injury appears to be mediated by both reactive oxygen metabolites and activated polymorphonuclear leukocytes.
B J, Zimmerman, D N, Granger
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Hyperoxia during reperfusion is a factor in reperfusion injury
Free Radical Biology and Medicine, 1989Imposition of ischemia should result in accumulation of lactic acid with an attendant drop in pH. Subsequent reperfusion would result in hyperoxia, in the affected tissue, due to the Bohr Effect. O2- should therefore be produced in greater than normal amounts, due to this transient hyperoxia, and may contribute to reperfusion injury.
M L, Wolbarsht, I, Fridovich
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Ischemia and reperfusion in pancreas
Microscopy Research and Technique, 1997Ischemic diseases of heart and brain are the primary causes of mortality in industrialized nations. The ischemic injury with the consecutive reperfusion is responsible for the disturbance of microcirculation with ensuing tissue damage and organ dysfunction.
T F, Hoffmann +3 more
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Emergency Nurse, 2006
In this article Nick Castle explains that, with significant improvements being made to the emergency management of cardiac patients, emergency nurses should challenge and develop their clinical practice to ensure patients receive prompt and evidence based treatment.
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In this article Nick Castle explains that, with significant improvements being made to the emergency management of cardiac patients, emergency nurses should challenge and develop their clinical practice to ensure patients receive prompt and evidence based treatment.
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Pulmonary Reperfusion Syndrome
The Annals of Thoracic Surgery, 1979"Reperfusion syndrome" of the lung may play a role in the pulmonary edema and hemorrhage that occur following pulmonary embolectomy, cardiopulmonary bypass, and shock. Bioenergetic, metabolic, and ultrastructural studies of canine lungs indicate that ventilated lung tissue could tolerate 5 hours of pulmonary arterial occlusion with minimal damage ...
D L, Modry, R C, Chiu
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Myocardial consequences of reperfusion
Progress in Cardiovascular Diseases, 1987OLLOWING THE introduction in the 1970s of coronary artery bypass surgery for emergency revascularization of patients with acute myocardial infarction, investigators began to report large hemorrhagic infarcts in some patients dying after surgery. Several experimental studies also reported possible deleterious consequences of reperfusion, but the ...
L C, Becker, G, Ambrosio
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1989
Thrombolysis with intravenous streptokinase, APSAC and tissue plasminogen activator has been shown to improve ventricular function and survival in patients with acute myocardial infarction (1–4). Despite these important advances several problems remain and we may not have achieved the optimal benefit from reperfusion therapy.
B. Pitt, B. Lucchesi
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Thrombolysis with intravenous streptokinase, APSAC and tissue plasminogen activator has been shown to improve ventricular function and survival in patients with acute myocardial infarction (1–4). Despite these important advances several problems remain and we may not have achieved the optimal benefit from reperfusion therapy.
B. Pitt, B. Lucchesi
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Reperfusion therapy for stroke
Australian and New Zealand Journal of Medicine, 1999AbstractStroke is a heterogenous disease, but about 85% of strokes are as a result of cerebral ischaemia due to arterial occlusion. It seems logical to assume that, as in myocardial infarction, treatment designed to dissolve clots should be helpful.We now have a substantial amount of data on the use of aspirin, heparin and thrombolytic drugs in the ...
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New England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
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Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
openaire +2 more sources