Results 1 to 10 of about 159,502 (205)
New England Journal of Medicine, 2007 Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M Yellon, Derek J Hausenloy
exaly +11 more sources
Clinical and procedural predictors of suboptimal myocardial reperfusion in primary percutaneous coronary intervention [PDF]
International Journal of Cardiology: Heart & Vasculature, 2019 Background: Suboptimal myocardial perfusion in primary PCI is associated with increased infarct size, left ventricular (LV) dysfunction and higher mortality rates as compared as those with optimal myocardial perfusion.
Adel H. Mahmoud +4 more
doaj +2 more sources
Impact of heart rate on myocardial salvage in timely reperfused patients with STSegment elevation myocardial infarction. new insights from cardiovascular magnetic resonance [PDF]
, 2015 BACKGROUND: Previous studies evaluating the progression of the necrotic wave in relation to heart rate were carried out only in animal models of ST-elevated myocardial infarction (STEMI).
AGATI, Luciano +8 more
core +10 more sources
Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]
PLoS ONE, 2014 Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong +4 more
doaj +1 more source
Bioactive Materials, 2022 Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high.
Tianjiao Zhao +6 more
doaj +1 more source
Frontiers in Immunology, 2021 Cardiomyocyte apoptosis in response to inflammation is a primary cause of myocardial ischemia-reperfusion injury (IRI). Nuclear factor erythroid 2 like 2 (Nrf2) reportedly plays an important role in myocardial IRI, but the underlying mechanism remains ...
Haijian Zhang +9 more
doaj +1 more source
Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1
Cell Death Discovery, 2022 Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has a critical role in the occurrence and progression of myocardial ischemia/reperfusion injury.
Qiong Xu +10 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang +9 more
doaj +1 more source
Endothelin in myocardial ischaemia and reperfusion [PDF]
Cardiovascular Research, 1997 Endothelin-1 (ET-1) is an extremely potent vasoconstrictor peptide derived from vascular endothelial cells. ET-1 can also be produced by other cell types such as smooth muscle cells and cardiomyocytes. Plasma levels of ET-1 are elevated during several different cardiovascular disorders like atherosclerosis, myocardial infarction and congestive heart ...
J, Pernow, Q D, Wang
openaire +2 more sources
Frontiers in Cardiovascular Medicine, 2022 Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia +9 more
doaj +1 more source