Results 41 to 50 of about 105,760 (306)

Lethal Myocardial “Reperfusion Injury” [PDF]

Journal of Thrombosis and Thrombolysis, 1997
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/48021/1/11239_2004_Article_255436 ...
openaire   +3 more sources

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Welsch, Ulrich, Sommerhoff, Christian P., Gilles, Stefanie, Zahler, Stefan, Becker, Bernhard F.   +4 more
core   +1 more source

Impact of an Interleukin-1 Receptor Antagonist and Erythropoietin on Experimental Myocardial Ischemia/Reperfusion Injury

The Scientific World Journal, 2012
Background. Revascularization of infarcted myocardium results in release of inflammatory cytokines mediating myocardial reperfusion injury and heart failure. Blockage of inflammatory pathways dampens myocardial injury and reduces infarct size.
Christina Grothusen, Angelika Hagemann, Tim Attmann, Jan Braesen, Ole Broch, Jochen Cremer, Jan Schoettler   +6 more
doaj   +1 more source

Reduction of myocardial infarction by postischemic administration of the calpain inhibitor A-705253 in comparison to the Na(+)/H(+) exchange inhibitor Cariporide (R) in isolated perfused rabbit hearts [PDF]

, 2008
The calpain inhibitor A-705253 and the Na(+)/H(+) exchange inhibitor Cariporide (R) were studied in isolated perfused rabbit hearts subjected to 60 min occlusion of the ramus interventricularis of the left coronary artery (below the origin of the first ...
Speth, Maria, Erdogan, Ali, Neuhof, Heinz, Neuhof, Christiane, Fabiunke, Verena, Fritz, Hans, Moeller, Achim, Tillmanns, Harald   +7 more
core   +1 more source

Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury [PDF]

PeerJ
Acute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium.
Wen Zhang, Qi Zhang, Yali Liu, Jianming Pei, Na Feng   +4 more
doaj   +2 more sources

Calpain: the regulatory point of myocardial ischemia-reperfusion injury

Frontiers in Cardiovascular Medicine, 2023
Calpain is a conserved cysteine protease readily expressed in several mammalian tissues, which is usually activated by Ca2+ and with maximum activity at neutral pH.
Guo-Yang Liu, Guo-Yang Liu, Guo-Yang Liu, Wan-Li Xie, Wan-Li Xie, Wan-Li Xie, Yan-Ting Wang, Yan-Ting Wang, Yan-Ting Wang, Lu Chen, Lu Chen, Lu Chen, Zhen-Zhen Xu, Zhen-Zhen Xu, Zhen-Zhen Xu, Yong Lv, Yong Lv, Yong Lv, Qing-Ping Wu, Qing-Ping Wu, Qing-Ping Wu   +20 more
doaj   +1 more source

Relation between Initial QRS Duration with Myocardial Reperfusion after Primary PCI

Majalah Kardiologi Indonesia, 2013
Background.Reperfusion therapy in acute myocardial infarction aims at early and sustained reperfusion of the myocardium at risk. However, even when TIMI flow 3 is achieved, some patients have less optimal reperfusion at myocardial tissue level.
doaj   +1 more source

Optical Activation of the Dorsal Horn of the Thoracic Spinal Cord Prevents Ventricular Arrhythmias in Acute Myocardial Ischemia-Reperfusion Rats

Frontiers in Cardiovascular Medicine, 2022
Background and ObjectivesSpinal cord stimulation can prevent myocardial ischemia and reperfusion arrhythmias, but the relevant neurons and mechanisms remain unknown.
Yong Wu, Zhongxu Luo, Zhengtao Hu, Kun Lv, Yinhua Liu, Deguo Wang, Deguo Wang   +6 more
doaj   +1 more source

Reduction of myocardial infarction by calpain inhibitors A-705239 and A-705253 in isolated perfused rabbit hearts [PDF]

, 2004
Two novel calpain inhibitors (A-705239 and A-705253) were studied in isolated perfused rabbit hearts subjected to 60-min occlusion of the ramus interventricularis of the left coronary artery (below the origin of the first diagonal branch), followed by ...
Speth, Maria, Deibele, Karin, Neuhof, Heinz, Lubisch, Wilfried, Möller, Achim, Neuhof, Christiane, Fabiunke, Verena, Fritz, Hans, Tillmanns, Harald   +8 more
core   +1 more source

Loss of PI3Kα Mediates Protection From Myocardial Ischemia–Reperfusion Injury Linked to Preserved Mitochondrial Function

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Identifying new therapeutic targets for preventing the myocardial ischemia–reperfusion injury would have profound implications in cardiovascular medicine.
Pavel Zhabyeyev, Brent McLean, Wesam Bassiouni, Robert Valencia, Manish Paul, Ahmed M. Darwesh, John M. Seubert, Saugata Hazra, Gavin Y. Oudit   +8 more
doaj   +1 more source