Results 51 to 60 of about 25,118 (249)
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn +10 more
wiley +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, EarlyView.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Brain Sciences, 2017 Excitation of intrinsic neurons of cerebellar fastigial nucleus (FN) renders brain tolerant to local and global ischemia. This effect reaches a maximum 72 h after the stimulation and lasts over 10 days.
Eugene V. Golanov +2 more
doaj +1 more source
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Archives of Plastic Surgery, 2013 Background Ischemic preconditioning has been shown to improve the outcomes of hypoxic tolerance of the heart, brain, lung, liver, jejunum, skin, and muscle tissues.
Ahmad Sukari Halim +3 more
doaj +1 more source
Quantitative Susceptibility Mapping of Kidney Stones: An Ex Vivo MRI Phantom Study
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To visualize and characterize the five most common kidney stone types based on their magnetic susceptibilities in MRI using QSM. Methods Three water‐based agar phantoms were constructed, containing a total of 53 ex vivo kidney stones of varying types and sizes.
Lion H. Mücke +8 more
wiley +1 more source
The Influence of Diabetes Mellitus in Myocardial Ischemic Preconditioning
Journal of Diabetes Research, 2016 Ischemic preconditioning (IP) is a powerful mechanism of protection discovered in the heart in which ischemia paradoxically protects the myocardium against other ischemic insults. Many factors such as diseases and medications may influence IP expression.
Paulo Cury Rezende +2 more
doaj +1 more source
Effects of ischemic preconditioning in a pig model of large-for-size liver transplantation
Clinics, 2015 OBJECTIVE: In most cases of pediatric liver transplantation, the clinical scenario of large-for-size transplants can lead to hepatic dysfunction and a decreased blood supply to the liver graft.
Antonio José Gonçalves Leal +8 more
doaj +1 more source
Andrology, EarlyView.ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source