Results 1 to 10 of about 63,266 (244)

Ischemic Tolerance—A Way to Reduce the Extent of Ischemia–Reperfusion Damage [PDF]

open access: yesCells, 2023
Individual tissues have significantly different resistance to ischemia–reperfusion damage. There is still no adequate treatment for the consequences of ischemia–reperfusion damage.
Rastislav Burda   +2 more
doaj   +4 more sources

Ischemic Tolerance Induced by Glial Cells [PDF]

open access: yesNeurochemical Research, 2022
AbstractIschemic tolerance is a phenomenon in which resistance to subsequent invasive ischemia is acquired by a preceding noninvasive ischemic application, and is observed in many organs, including the brain, the organ most vulnerable to ischemic insult.
Schuichi Koizumi, Koizumi Schuichi
exaly   +4 more sources

Role of homocysteine in the ischemic stroke nad development of ischemic tolerance [PDF]

open access: yesFrontiers in Neuroscience, 2016
Homocysteine (Hcy) is a toxic, sulfur-containing intermediate of methionine metabolism. Hyperhomocysteinemia (hHcy), as a consequence of impaired Hcy metabolism or defects in crucial co-factors that participate in its recycling, is assumed as an ...
Jan Lehotsky   +7 more
doaj   +4 more sources

Dynamic changes in DNA methylation in ischemic tolerance [PDF]

open access: yesFrontiers in Neurology, 2015
Epigenetic mediators of gene expression are hypothesized to regulate transcriptomic responses to preconditioning ischemia and ischemic tolerance. Here we utilized a methyl-DNA enrichment protocol and sequencing (ChIP-seq) to identify patterns of DNA ...
Robert eMeller   +2 more
doaj   +4 more sources

Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors [PDF]

open access: yesBiomolecules, 2022
In this study, we characterize biophysical changes in NMDA receptor function in response to brief non-injurious ischemic stress (ischemic preconditioning).
Mian Xie   +6 more
doaj   +2 more sources

Genome-Wide Transcription Analysis of Electroacupuncture Precondition-Induced Ischemic Tolerance on SD Rat With Ischemia–Reperfusion Injury [PDF]

open access: yesFrontiers in Genetics, 2021
Acupuncture promotes the recovery of neurological function by the overall improvement of ischemic brain injury. It is not only regarded as a rehabilitative treatment but also a pretreatment method for stroke.
Shuping Fu   +11 more
doaj   +2 more sources

Immune mechanisms in cerebral ischemic tolerance [PDF]

open access: yesFrontiers in Neuroscience, 2014
Stressor-induced tolerance is a central mechanism in the response of bacteria, plants, and animals to potentially harmful environmental challenges.
Lidia eGarcia-Bonilla   +4 more
doaj   +4 more sources

Ischemic Preconditioning Modulates the Peripheral Innate Immune System to Promote Anti-Inflammatory and Protective Responses in Mice Subjected to Focal Cerebral Ischemia

open access: yesFrontiers in Immunology, 2022
The development of tolerance triggered by a sublethal ischemic episode (preconditioning, PC) involves a complex crosstalk between neurons, astrocytes and microglia, although the role of the peripheral immune system in this context is largely unexplored ...
Diana Amantea   +7 more
doaj   +1 more source

The Cholinergic Pathway and MitoKATP Induce UCP4 Expression Involved in Neuroprotection of FN Stimulation in Rats

open access: yesStroke: Vascular and Interventional Neurology, 2022
Background Electrical stimulation of the cerebellar fastigial nucleus (FN) reduces the infarct size induced by middle cerebral artery occlusion in rats.
Yasuko Fukushi   +5 more
doaj   +1 more source

Mechanisms and Prospects of Ischemic Tolerance Induced by Cerebral Preconditioning [PDF]

open access: yesInternational Neurourology Journal, 2010
In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance.
Mohammad Iqbal Hossain Bhuiyan   +1 more
doaj   +1 more source

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