Results 41 to 50 of about 80,518 (304)
The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological preconditioning [PDF]
Includes bibliographical references (leaves 150-177).Ischemic preconditioning is a protective mechanism whereby repetitive transient ischaemia confer protection against the subsequent prolonged lethal ischaemia that is observed during myocardial ...
Suleman, Naushaad
core +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Optimization of oxidative preconditioning of hWJ-MSCs to overcome oxidative stress
Aim. It has been shown that biological properties of MSCs can be modulated by preconditioning of MSCs under specific culture conditions. Our study aimed to evaluate the effects of different H2O2 concentrations during oxidative preconditioning of hWJ ...
M. V. Kovalchuk +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Regulation of gap junction function; the role of nitric oxide. [PDF]
Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Kovács Mária +15 more
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The effect of preconditioning cells under osmotic stress on high alcohol production [PDF]
This paper focuses on the research into the influence of salt on physiology of the yeast, Saccharomyces cerevisiae. Specifically, the work focused on how NaCl affected the growth, viability and fermentation performance of this yeast in laboratory ...
Logotetis Stilijanos +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia
Substantial evidence has established that a short sub-lethal brain ischemia applied before a prolonged harmful ischemic episode confers ischemic neuroprotection, a phenomenon named ischemic preconditioning.
Giuseppe Pignataro +7 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source

