Results 91 to 100 of about 1,317,566 (363)

Financial Distress and its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent chronic use of expensive disease modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or non‐inflammatory musculoskeletal disease (NIMSKD) completing the Functional
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

The role of fasting versus nonfasting triglycerides in ischemicstroke: a systematic review

Frontiers in Neurology, 2010
Objective: To synthesize results from pertinent studies and determine if fasting and/or nonfasting triglycerides are a risk factor for ischemic stroke.
Christopher Leonards, Martin Ebinger, Martin Ebinger, Jana Batluk, Uwe Malzahn, Peter Heuschmann, Matthias Endres, Matthias Endres   +7 more
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan

Journal of Biomedical Science, 2012
Background The association between ischemic stroke and 2 single nucleotide polymorphisms (SNPs) on chromosome 12p13, rs12425791 and rs11833579 appears inconsistent across different samples.
Hsieh Yi-Chen, Seshadri Sudha, Chung Wen-Ting, Hsieh Fang-I, Hsu Yi-Hsiang, Lin Huey-Juan, Tseng Hung-Pin, Lien Li-Ming, Bai Chyi-Huey, Hu Chaur-Jong, Jeng Jiann-Shing, Tang Sung-Chun, Chen Chin-I, Yu Chia-Chen, Chiou Hung-Yi   +14 more
doaj   +1 more source

Sonothrombolysis for Ischemic Stroke

Journal of Cardiovascular Development and Disease
Stroke is a major cause of death and disability globally, with ischemic stroke being the predominant mechanism. While spontaneous recanalization may occur, significant neuronal injury would have occurred in the interim. Intravenous thrombolysis administered within the first 4.5 h after stroke onset and endovascular thrombectomy within 24 h in patients ...
Narayanaswamy Venketasubramanian, Leonard L. L. Yeo, Benjamin Tan, Bernard P. L. Chan   +3 more
openaire   +3 more sources

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Role of gut microbiota in ischemic stroke: A narrative review of human and animal studies

Neuroprotection
The high incidence, mortality, and disability associated with ischemic stroke pose a significant threat to human health. The intestinal microbiota significantly influences the onset, progression, and prognosis of ischemic stroke.
Guangtang Chen, Xiaolin Du, Junshuan Cui, Jiaquan Song, Mingsong Xiong, Xi Zeng, Hua Yang, Kaya Xu   +7 more
doaj   +1 more source

SARS2-CoV-2 and Stroke in a New York Healthcare System

Stroke, 2020
Background and Purpose: With the spread of coronavirus disease 2019 (COVID-19) during the current worldwide pandemic, there is mounting evidence that patients affected by the illness may develop clinically significant coagulopathy with thromboembolic ...
S. Yaghi, Koto Ishida, J. Torres, B. M. Mac Grory, E. Raz, Kelley A. Humbert, N. Henninger, Tushar Trivedi, K. Lillemoe, S. Alam, Matthew D Sanger, Sun Kim, E. Scher, S. Dehkharghani, M. Wachs, O. Tanweer, Frank Volpicelli, Brian P. Bosworth, A. Lord, J. Frontera   +19 more
semanticscholar   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source