Results 41 to 50 of about 967,967 (261)

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke [PDF]

open access: yes, 2012
Genome-wide association studies (GWAS) have not consistently detected replicable genetic risk factors for ischemic stroke, potentially due to etiological heterogeneity of this trait.
Rodney J Scott   +271 more
core   +1 more source

Glial and axonal body fluid biomarkers are related to infarct volume, severity, and outcome. [PDF]

open access: yes, 2008
Body fluid biomarkers of central nervous system damage may help improve the prognostic and diagnostic accuracy in ischemic stroke. We studied 53 patients.
Stock, M   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial [PDF]

open access: yes, 2008
<p><b>Background and Purpose</b>: Elevated serum uric acid level is associated with poor outcome and increased risk of recurrent events after stroke.
Lees, K.R.   +6 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Proportions, trends, and outcomes of posterior circulation ischemic stroke in the United States

open access: yesFrontiers in Neurology
BackgroundPosterior circulation ischemic stroke has been previously studied in single-center and multicenter registries. The contemporary proportions, trends, and outcomes of posterior circulation ischemic stroke at a national level are not known ...
Adnan I. Qureshi   +9 more
doaj   +1 more source

The Predictive Value of Neurofilament Light Chain in Ischemic Stroke Severity and Short Term Outcome [PDF]

open access: yesZagazig University Medical Journal
:Background: Ischemic stroke is one of the most prevalent diseases affecting the brain with negative impact on quality of life, daily activity of ischemic stroke survivors, their families and society.
Rania Helal   +3 more
doaj   +1 more source

Animal Models of Ischemic Stroke with Different Forms of Middle Cerebral Artery Occlusion

open access: yesBrain Sciences, 2023
Ischemic stroke is a common type of stroke that significantly affects human well-being and quality of life. In order to further characterize the pathophysiology of ischemic stroke and develop new treatment strategies, ischemic stroke models with ...
Lang Zeng   +6 more
doaj   +1 more source

Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial [PDF]

open access: yes, 2006
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant demonstrated to reduce disability from ischemic stroke. We conducted analyses on additional end points and sensitivity analyses to confirm our findings.
Lees, K.R.   +11 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

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