Results 61 to 70 of about 924,610 (305)

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke [PDF]

, 2012
Genome-wide association studies (GWAS) have not consistently detected replicable genetic risk factors for ischemic stroke, potentially due to etiological heterogeneity of this trait.
Rodney J Scott, Barlera, S., Brott, TG, Verhaaren, BF, Ross Baker, Furie, Karen L., Psaty, Bruce M., Mitchell, Braxton D., Brott, Thomas G., Boerwinkle, E., Scott, Rodney J., Markus, Hugh S, Fornage, Myriam, Lincz, Lisa F, Matthew Traylor, Oldmeadow, C., Attia, J., McEvoy, M., Rothwell, Peter M., Andreas Gschwendtner, Rosand, Jonathan, Cole, J.W., Worrall, Bradford B, Holliday, Elizabeth G, Levi, C., Bis, Joshua C, Robert D Brown, Mark McEvoy, Koblar, S.A., Parsons, Mark W., Koblar, Simon A, Pankaj Sharma, Benjamin F J Verhaaren, Sharma, P, Parati, E.A., Worrall, BB, Moscato, Pablo, Evans, TJ, Steve Bevan, Farrall, M, Rothwell, Peter M, Brown, RD, Brown, Robert D, William J Devan, Bradford B Worrall, Boerwinkle, Eric, Lisa F Lincz, Levi, Christopher, Nalls, Michael A., Stefansson, K, Maguire, Jane M, Sudlow, Catherine; id_orcid, Wiggins, Kerri L., Martin Farrall, Longstreth, W T, Moscato, P, Psaty, Bruce M, John W Cole, Boerwinkle, E, Brown, Robert D., Biros, Erik, Furie, K.L., Maguire, J.M., Bis, JC, Simona Barlera, Kari Stefansson, Sturm, Jonathan W, Peel, R, Rothwell, P.M., Jannes, J, Mark W Parsons, Thomas H Mosley, M Arfan Ikram, Christopher Levi, Jannes, Jim, McEvoy, Mark, Devan, William J, Dichgans, M., Lewis, Martin D, Unnur Thorsteinsdottir, Boncoraglio, Giorgio B, Baker, R, Peter M Rothwell, Golledge, J, Hankey, GJ, Jonathan Rosand, W T Longstreth, Holliday, EG, Rosand, J., James F Meschia, Cheng, YC, Wiggins, K.L., Maguire, JM, Verhaaren, B.F.J., Meschia, JF, Graeme J Hankey, Gudmar Thorleifsson, Scott, R.J., Levi, C, Scott, Rodney J, Rainer Malik, Koblar, SA, Verhaaren, Ben, Bis, J.C., Hankey, Graeme J., Smith, W., Barlera, S, Lewis, M.D., Devan, William J., Bevan, S, Jane M Maguire, Wiggins, KL, Boncoraglio, Giorgio B., Verhaaren, BFJ, Sudlow, C, Furie, Karen L, Grétarsdóttir, S, Lincz, LF, Worrall, Bradford B., Mitchell, Braxton D, Mosley, Thomas H, Thomas G Brott, Jannes, J., Malik, R., Boncoraglio, GB, Nalls, M.A., Koblar, S., Thorsteinsdottir, Unnur, Fornage, M., Wayne Smith, Traylor, M, Boncoraglio, G.B., Biros, E., Mosley, TH, Attia, John, Grétarsdóttir, S., Oldmeadow, Christopher, Parati, Eugenio A, Stefansson, K., Wiggins, Kerri L, Markus, HS, Kerri L Wiggins, Devan, WJ, Hugh S Markus, Bis, Joshua C., Ikram, M Arfan, Ikram, M.A., Rosand, J, Dichgans, M, Verhaaren, Benjamin F J, McEvoy, M, Farrall, M., Thorleifsson, G, Malik, R, Longstreth, W.T., Grétarsdóttir, Sólveig, Mitchell, BD, Golledge, Jonathan, Giorgio B Boncoraglio, Baker, Ross, Tiffany-Jane Evans, Holliday, Elizabeth G., Sturm, Jonathan W., Erik Biros, Farrall, Martin, Sharma, Pankaj, Brott, T.G., Stefansson, Kari, Karen L Furie, Rothwell, PM, Golledge, J., Lewis, Martin D., Ikram, M. Arfan, Sharma, P., Peel, Roseanne, Martin Dichgans, Cheng, Yu-Ching, Smith, Wayne, Jonathan W Sturm, Parati, EA, Attia, J, Cotlarciuc, Ioanna, Barlera, Simona, Cathie Sudlow, Nalls, MA, Cheng, Y-C, Fornage, M, Baker, R., Oldmeadow, C, Cotlarciuc, Ioana, Gschwendtner, A., Bevan, Steve, Thorsteinsdottir, U., Yu-Ching Cheng, Lewis, M., Maguire, Jane M., Ikram, MA, Smith, W, Longstreth, WT, Holliday, E.G., Scott, RJ, Worrall, B.B., Meschia, James F, Gschwendtner, Andreas, Dichgans, Martin, Lewis, MD, Jim Jannes, Thorleifsson, G., Michael A Nalls, Devan, W.J., Gschwendtner, A, Brown, Robert D., Jr., Roseanne Peel, Bruce M Psaty, Cotlarciuc, I, Eugenio A Parati, Brown, R.D., Holliday, E., Hankey, G.J., Simon A Koblar, Elizabeth G Holliday, Thorleifsson, Gudmar, Thorsteinsdottir, U, Evans, T-J, Sudlow, C., Christopher Oldmeadow, Verhaaren, Benjamin F.J., John Attia, Lincz, L.F., Mosley, Thomas H., Markus, H.S., Psaty, BM, Pablo Moscato, Sólveig Grétarsdóttir, Nalls, Michael A, Sturm, JW, Parsons, MW, Peel, R., Mosley, T.H., Jonathan Golledge, Martin D Lewis, Sturm, J.W., Parati, Eugenio A., Cole, John W, Ikram, Arfan, Traylor, M., Psaty, B.M., Hankey, Graeme J, Biros, E, Meschia, J.F., Joshua C Bis, Ioana Cotlarciuc, Mitchell, B.D., Markus, Hugh S., Myriam Fornage, Eric Boerwinkle, Brott, Thomas G, Bevan, S., Moscato, P., Parsons, Mark W, Sudlow, Cathie, Cole, John W., Furie, KL, Parsons, M.W., Koblar, Simon A., Lincz, Lisa F., Meschia, James F., Malik, Rainer, Braxton D Mitchell, Cotlarciuc, I., Evans, Tiffany-Jane, Cole, JW, Traylor, Matthew   +272 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Risk factors for periprocedural ischemic stroke following endovascular treatment of intracranial aneurysms

Chinese Neurosurgical Journal, 2021
Background The aim of this study was to comprehensively evaluate the risk factors of periprocedural ischemic stroke associated with endovascular treatment of intracranial aneurysms using a real-world database.
Yisen Zhang, Chao Wang, Zhongbin Tian, Wei Zhu, Wenqiang Li, Xinjian Yang, Jian Liu, Ying Zhang   +7 more
doaj   +1 more source

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial [PDF]

, 2008
<p><b>Background and Purpose</b>: Elevated serum uric acid level is associated with poor outcome and increased risk of recurrent events after stroke.
Lees, K.R., Walters, M.R., Weir, C.J., Dawson, J., Muir, S.W., Sattar, N., Harrow, C.   +6 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]

, 2012
Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.
Herve, Dominique, Jouvent, Eric, Duering, Marco, Chabriat, Hugues, Allili, Nassira, Yao, Ming, Dichgans, Martin   +6 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source