Results 51 to 60 of about 404,120 (314)

Microbiome and ischemic stroke: A systematic review.

PLoS ONE, 2021
BackgroundIschemic stroke is one of the non-communicable diseases that contribute to the significant number of deaths worldwide. However, the relationship between microbiome and ischemic stroke remained unknown.
Yee Teng Lee, Nor Ismaliza Mohd Ismail, Loo Keat Wei   +2 more
doaj   +1 more source

The Desmoteplase In Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase [PDF]

, 2005
<p><b>Background and Purpose:</b> Most acute ischemic stroke patients arrive after the 3-hour time window for recombinant tissue plasminogen activator (rtPA) administration.
Fischer, M., Eliasziw, M., Lees, K.R., Kaste, M., Albers, G., Al, R.Y., Hacke, W., Furlan, A., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats [PDF]

, 2009
<p><b>Background and Purpose:</b> Stroke-prone spontaneously hypertensive rats (SHRSP) are a highly pertinent stroke model with increased sensitivity to focal ischemia compared with the normotensive reference strain (Wistar-Kyoto rats ...
Dominiczak, Anna F., Graham, Delyth, Macrae, I. Mhairi, Gallagher, Lindsay, Gsell, Willy, McCabe, Christopher   +5 more
core   +1 more source

HDAC4 in ischemic stroke: mechanisms and therapeutic potential

Clinical Epigenetics, 2018
Stroke is one of the leading causes of death and disability worldwide, and the majority of the cases are ischemic stroke. However, it still lacks effective treatment except for thrombolytic therapy in an extremely narrow time window.
Qingsheng Kong, Yongnan Hao, Xin Li, Xin Wang, Bingyuan Ji, Yili Wu   +5 more
doaj   +1 more source

The Virtual International Stroke Trials Archive [PDF]

, 2007
Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal.
Donnan, Geoffrey A., Kaste, M., HENNERICI, Michael G, Teal, P., Gregson, B.A., Hacke, Werner, Marler, J.R., Marler, John R., Fisher, M., GREGSON, Barbara A, Wahlgren, Nils-Gunnar, Curram, John, Grotta, J., MARLER, John R, Davis, Stephen M., Sacco, Ralph L., Donnan, G.A., Myzoon, Ali, Bath, Philip M.W., Teal, Philip, WEIR, Christopher J, Weir, C.J., Gregson, Barbara A., Fisher, Marc, Hommel, Marc, Hacke, W., BATH, Philip M. W, Sacco, R.L., Diener, Hans-Christoph, Warach, S., DONNAN, Geoffrey A, Hennerici, Michael G., Wahlgren, N.-G., Lees, K.R., Grotta, James, Hennerici, M.G., Kaste, Markku, Weir, Christopher J., Warach, Steven, Lees, Kennedy R., DAVIS, Stephen M, Bath, P.M.W., Ali, M., Curram, J., Diener, H.-C., Ali, Myzoon, Davis, S.M., SACCO, Ralph L, Hommel, M., LEES, Kennedy R   +49 more
core   +1 more source

Associations of proinflammatory cytokines with the risk of recurrent stroke [PDF]

, 2008
<p><b>Background and Purpose:</b> There are few reports on proinflammatory cytokines and risk of primary or recurrent stroke. We studied the association of interleukin (IL)-6, IL-18, and tumor necrosis factor-α (TNF-α) with recurrent ...
Welsh, P., Chalmers, J., Lowe, G.D., Welsh, P, Woodward, M, Lowe, GD, MacMahon, SW, Neal, B.C., Campbell, DJ, Neal, BC, MacMahon, S.W., Rumley, A., Campbell, D., Chalmers, J, MacMahon, Stephen, Rumley, A, Woodward, M.   +16 more
core   +1 more source

Thrombolysis and Thrombectomy in Acute Ischemic Stroke [PDF]

, 2023
In the treatment of acute stroke, thrombolysis and thrombectomy have proven to be highly effective. Many patients have seen significant improvement after reperfusion therapy. This reprint aims to address current knowledge gaps and promote advancements in

core   +1 more source

A study on structural imaging changes and serum neurofilament light chain (NfL) levels in individuals with white matter hyperintensities, combining imaging techniques with biomarker analysis

IBRO Neuroscience Reports
Objective: To elucidate the association between serum neurofilament light chain (NfL) levels and structural brain alterations in individuals exhibiting white matter hyperintensities (WMHs), as well as to investigate the potential utility of serum NfL as ...
Meini Wu, Zihao Li, Yuhang Ren, Siou Li, Weina Zhao, Jian Xing, Jiangnan Yi, Fengze Zhao, Changhao Yin   +8 more
doaj   +1 more source

Ischemic Stroke During the Pandemic in a Secondary Care Hospital: COVID-19 and Its Collateral Effects

Batı Karadeniz Tıp Dergisi, 2023
Aim: Ischemic stroke is among the leading causes of death and disability. Although recent studies haveshown a possible relationship between COVID-19 and ischemic stroke, the effect of the pandemic period,which may be another factor in the increase of ...
Elif Uygur Kucukseymen, Ebru Balaban, Şenay Öztürk Durmaz   +2 more
doaj   +1 more source

Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]

, 2009
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A., Lees, K.R., Kasner, S.E., Messe, S.R., Cucchiara, B., Levine, S.R., Lyden, P., Sansing, L., Tanne, D.   +8 more
core   +1 more source