A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
Advanced Science, EarlyView.This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
Regional and Socioeconomic Disparities in Frailty Across Tasmania: Evidence From Island Study Linking Ageing and Neurodegenerative Disease. [PDF]
Australas J AgeingLou Z +7 more
europepmc +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
The role of culture and literacy in screening for major neurocognitive disorders for elderly patients on Reunion Island: A cross-sectional study on the concordance between the French Mini-Mental State Examination and an adapted version (MMS-Run). [PDF]
J Alzheimers DisChevy A +11 more
europepmc +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Island Studies Journal 12(1), Book Reviews
Island Studies Journal, 2017 Island Studies Journal
doaj +1 more source
Influence of land-use history and ENSO on the flora of the Southern Line Islands. [PDF]
PLoS OneNerfa L +5 more
europepmc +1 more source
Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging
Advanced Science, EarlyView.Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika +22 more
wiley +1 more source
Island Studies Journal 4(1), Book Reviews
Island Studies Journal, 2009 Island Studies Journal
doaj +1 more source
Correction to "Terrestrial Chemical Cues Help Coral Reef Fish Larvae Locate Settlement Habitat Surrounding Islands". [PDF]
Ecol Evoleuropepmc +1 more source