Results 1 to 10 of about 13,873 (221)
Humanized Culture Medium for Clinical Expansion of Human Erythroblasts [PDF]
Cell Transplantation, 2010 Ex vivo-generated erythroblasts represent alternative transfusion products. However, inclusion of bovine components in media used for their growth precludes clinical use, highlighting the importance of developing culture media based on pharmaceutical ...
Giovanni Migliaccio +2 more
exaly +3 more sources
Acta Biomedica Scientifica, 2022 Introduction. Bone marrow erythroblasts produce a wide range of cytokines with opposite biological effects. This may be due to a change in the spectrum of production of immunoregulatory mediators during differentiation and small qualitative and ...
K. V. Nazarov +7 more
doaj +3 more sources
Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts [PDF]
Haematologica, 2020 Erythropoiesis is one of the most efficient cellular processes in the human body producing approximately 2.5 million red blood cells every second.
Lea A. Hampton-O’Neil +5 more
doaj +4 more sources
Scientific Reports, 2017 Hematopoietic ontogeny is characterized by distinct primitive and definitive erythroid lineages. Definitive erythroblasts mature and enucleate extravascularly and form a unique membrane skeleton, composed of spectrin, 4.1R-complex, and ankyrinR-complex ...
Yu-Shan Huang +10 more
doaj +2 more sources
Cell Reports, 2021 Summary: Metabolic support was long considered to be the only developmental function of hematopoiesis, a view that is gradually changing. Here, we disclose a mechanism triggered during neurulation that programs brain development by donation of ...
Filip Vujovic, Ramin M Farahani
exaly +3 more sources
Erythroblasts Promote the Development of a Suppressive Lymphocyte Phenotype via Treg Induction and PD1 Upregulation on the Surfaces of B-Cells: A Study on the Subpopulation-Specific Features of Erythroblasts [PDF]
Current Issues in Molecular BiologyThis study identifies the novel effects of soluble factors derived from murine erythroblasts on lymphoid cell phenotypes. These effects were observed following the treatment of splenic mononuclear cells with erythroblast-conditioned media received from ...
Kirill Nazarov +3 more
doaj +2 more sources
Stem Cell Reports, 2016 The development of human erythroid cells has been mostly examined in models of adult hematopoiesis, while their early derivation during embryonic and fetal stages is largely unknown.
Bin Mao, Wencui Sun, Mowen Lai
exaly +3 more sources
STAR Protocols, 2022 Summary: This protocol describes the generation and characterization of human induced pluripotent stem cells (hiPSCs) from erythroblasts. A key difference with classical protocols is the reprogramming of erythroblasts from a simple blood draw as opposed ...
Sylvain Perriot +3 more
doaj +2 more sources
Characterization of first trimester fetal erythroblasts for non-invasive prenatal diagnosis
Molecular Human Reproduction, 2003 Isolating fetal erythroblasts from first trimester maternal blood offers a promising non-invasive alternative for prenatal diagnosis. The aim of this study was to characterize the biological properties of first trimester primitive erythroblasts to ...
Mahesh Choolani +2 more
exaly +2 more sources
Visual Detection of Malaria Parasite-Parasitized Erythroblasts in Peripheral Blood via Immunization-Based Model [PDF]
VaccinesBackground: Erythroblasts have recently been identified as host cells for malarial parasites, revealing a previously underappreciated host–parasite interaction.
Kumpei Ito +18 more
doaj +2 more sources