Results 1 to 10 of about 11,797 (185)

Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics

open access: yesCell Reports, 2021
Summary: Metabolic support was long considered to be the only developmental function of hematopoiesis, a view that is gradually changing. Here, we disclose a mechanism triggered during neurulation that programs brain development by donation of ...
Filip Vujovic, Ramin Farahani
exaly   +3 more sources

Erythroblasts Promote the Development of a Suppressive Lymphocyte Phenotype via Treg Induction and PD1 Upregulation on the Surfaces of B-Cells: A Study on the Subpopulation-Specific Features of Erythroblasts [PDF]

open access: yesCurrent Issues in Molecular Biology
This study identifies the novel effects of soluble factors derived from murine erythroblasts on lymphoid cell phenotypes. These effects were observed following the treatment of splenic mononuclear cells with erythroblast-conditioned media received from ...
Kirill Nazarov   +3 more
doaj   +2 more sources

Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36

open access: yesStem Cell Reports, 2016
The development of human erythroid cells has been mostly examined in models of adult hematopoiesis, while their early derivation during embryonic and fetal stages is largely unknown.
Jiaxi Zhou, Bo Chen, Mowen Lai
exaly   +3 more sources

Visual Detection of Malaria Parasite-Parasitized Erythroblasts in Peripheral Blood via Immunization-Based Model [PDF]

open access: yesVaccines
Background: Erythroblasts have recently been identified as host cells for malarial parasites, revealing a previously underappreciated host–parasite interaction.
Kumpei Ito   +18 more
doaj   +2 more sources

Humanized Culture Medium for Clinical Expansion of Human Erythroblasts

open access: yesCell Transplantation, 2010
Ex vivo-generated erythroblasts represent alternative transfusion products. However, inclusion of bovine components in media used for their growth precludes clinical use, highlighting the importance of developing culture media based on pharmaceutical ...
Valentina Tirelli   +2 more
exaly   +2 more sources

Environmental Nanoparticles Reach Human Fetal Brains

open access: yesBiomedicines, 2022
Anthropogenic ultrafine particulate matter (UFPM) and industrial and natural nanoparticles (NPs) are ubiquitous. Normal term, preeclamptic, and postconceptional weeks(PCW) 8–15 human placentas and brains from polluted Mexican cities were analyzed by TEM ...
Lilian Calderón-Garcidueñas   +10 more
doaj   +1 more source

Parvovirus Infection Causing Aplastic Anaemia in an Immunocompetent Patient Diagnosed by Bone Marrow Aspiration Cytology [PDF]

open access: yesNational Journal of Laboratory Medicine, 2021
Human Parvovirus infection is associated with transient aplastic crisis as a most common complication in chronic haemolytic anaemia patients. Very few case reports are available regarding aplastic crisis in immunocompetent patients. Here the authors are
Ranjana Giri, Urmila Senapati
doaj   +1 more source

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera

open access: yesScientific Reports, 2021
Polycythaemia vera (PV) is a haematological disorder caused by an overproduction of erythroid cells. To date, the molecular mechanisms involved in the disease pathogenesis are still ambiguous.
Chartsiam Tipgomut   +9 more
doaj   +1 more source

Production of immunoregulatory molecules by induced erythroblasts at various stages of cell differentiation

open access: yesActa Biomedica Scientifica, 2022
Introduction. Bone marrow erythroblasts produce a wide range of cytokines with opposite biological effects. This may be due to a change in the spectrum of production of immunoregulatory mediators during differentiation and small qualitative and ...
K. V. Nazarov   +7 more
doaj   +1 more source

Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts

open access: yesFrontiers in Genetics, 2020
Erythropoiesis of human hematopoietic stem cells (HSCs) maintains generation of red blood cells throughout life. However, little is known how human erythropoiesis is regulated by long non-coding RNAs (lncRNAs). By using ChIRP-seq, we report here that the
Waritta Sawaengdee   +6 more
doaj   +1 more source

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