Results 31 to 40 of about 13,873 (221)
A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease
Background Cells respond to stress stimuli through a number of response pathways, of which one of the most important and well characterized is the unfolded protein response.
Pathrapol Lithanatudom +5 more
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Introduction: Bisphenol A (BPA) is a substance widely used in industry for the production of polycarbonates and epoxy resins used in packaging and containers for beverages, contact lenses, compact discs (CDs), window panes, and many other elements.
Snarska Anna +4 more
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The study of human erythropoiesis in health and disease requires a robust culture system that consistently and reliably generates large numbers of immature erythroblasts that can be induced to differentiate synchronously.
Emile van den Akker +4 more
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No Mitoses in Basophilic Erythroblasts
SummaryIn the rabbit, under conditions in which mitoses accumulated in the acidophilic erythroblasts, none were observed in the basophilic erythroblasts. On the basis of certain assumptions, the basophilic erythroblasts were divided into two size classes: of average long diameters (as measured here) 10.3 and 8.4 nm.
H, Borsook, S, Jiggins
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During erythropoiesis, the molecular chaperone alpha-hemoglobin-stabilizing protein (AHSP) sequesters free alpha-hemoglobin (αHb) and prevents precipitation of excess αHb.
Julia Walczak +2 more
doaj +1 more source
Peripheral cisternae and double membranes (PCDMs) in erythroid cells are a landmark of type II congenital dyserythropoietic anemia (CDA). To gain further insights into the mechanism of dyserythropoiesis, erythroblasts and erythrocytes in bone marrow were
Yong-Xin Ru +3 more
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CD8+ T cell activation by murine erythroblasts infected with malaria parasites [PDF]
Recent studies show that some human malaria parasite species Plasmodium falciparum and P. vivax parasitize erythroblasts; however, the biological and clinical significance of this is unclear. To investigate further, we generated a rodent malaria parasite
Imai, Takashi +8 more
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Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies.
Soo-Been Jeon +9 more
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The fetal liver (FL) is the key erythropoietic organ during fetal development, but knowledge on human FL erythropoiesis is very limited. In this study, we sorted primary erythroblasts from FL cells and performed RNA sequencing (RNA-seq) analyses.
Yongshuai Han +8 more
doaj +1 more source
THE METABOLISM OF HUMAN ERYTHROBLASTS [PDF]
The metabolism of human nucleated red blood cells has not previously been determined because of difficulties in procuring material. In most anemias the number of nucleated erythrocytes in the blood is so small in relation to the number of non-nucleated erythrocytes that the metabolism of the former is obscured by that of the latter.
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