Results 31 to 40 of about 23,516 (234)
Scientific Reports, 2022 β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications.
Pornthip Chaichompoo +9 more
doaj +1 more source
Fetal cells in maternal circulation : fetal cell separation and FISH analysis [PDF]
, 2005 This work focuses on the isolation of fetal cells from the blood of pregnant women, with the aim of developing safe, efficacious, non-invasive alternatives for prenatal diagnosis.
Babochkina, Tatiana Ivanovna
core +1 more source
Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts
Frontiers in Physiology, 2020 The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic ...
Francesca Aglialoro +4 more
semanticscholar +1 more source
Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]
, 1964 For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
core +1 more source
Scientific Reports, 2020 The molecular mechanisms involved in the terminal differentiation of erythroblasts have been elucidated by comparing enucleation and cell division. Although various similarities and differences between erythroblast enucleation and cytokinesis have been ...
Kumi Ubukawa +8 more
semanticscholar +1 more source
Role of apoptotic and anti-apoptotic mechanisms in erythroblast differentiation [PDF]
, 2004 The present study focuses on deciphering the differentiation mechanisms of erythroid cells. In particular, the involvement of apoptotic mechanisms in erythroblast differentiation and enucleation was examined.
Hristoskova, Sashka
core +1 more source
FGF23 from erythroblasts promotes hematopoietic progenitor mobilization.
Blood, 2020 Fibroblast growth factor-23 (FGF23) hormone is produced by bone-embedded osteocytes and regulates phosphate homeostasis in kidneys. We found that granulocyte colony-stimulating factor (G-CSF) administration in mice induced a rapid and tremendous increase
S. Ishii +12 more
semanticscholar +1 more source
From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals
Frontiers in Physiology, 2017 Erythropoiesis occurs mostly in bone marrow and ends in blood stream. Mature red blood cells are generated from multipotent hematopoietic stem cells, through a complex maturation process involving several morphological changes to produce a highly ...
Martina Moras, S. Lefevre, M. Ostuni
semanticscholar +1 more source
EPAS1 regulates proliferation of erythroblasts in chronic mountain sickness.
Blood Cells, Molecules & Diseases, 2020 Excessive erythrocytosis (EE) is a characteristic of chronic mountain sickness (CMS). Currently, the pathogenesis of CMS remains unclear. This study was intended to investigate the role of EPAS1 in the proliferation of erythroblasts in CMS.
Hui-Hui Liu +12 more
semanticscholar +1 more source
Microfluidic assay of the deformability of primitive erythroblasts [PDF]
, 2017 Primitive erythroblasts (precursors of red blood cells) enter vascular circulation during the embryonic period and mature while circulating. As a result, primitive erythroblasts constantly experience significant hemodynamic shear stress.
Sitong Zhou +11 more
core +1 more source