Results 31 to 40 of about 13,873 (221)

A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease

open access: yesHaematologica, 2010
Background Cells respond to stress stimuli through a number of response pathways, of which one of the most important and well characterized is the unfolded protein response.
Pathrapol Lithanatudom   +5 more
doaj   +1 more source

Cytological evaluation of the influence of high and low doses of bisphenol A on an erythroblastic cell line of porcine bone marrow

open access: yesJournal of Veterinary Research, 2018
Introduction: Bisphenol A (BPA) is a substance widely used in industry for the production of polycarbonates and epoxy resins used in packaging and containers for beverages, contact lenses, compact discs (CDs), window panes, and many other elements.
Snarska Anna   +4 more
doaj   +1 more source

The majority of the in vitro erythroid expansion potential resides in CD34− cells, outweighing the contribution of CD34+ cells and significantly increasing the erythroblast yield from peripheral blood samples

open access: yesHaematologica, 2010
The study of human erythropoiesis in health and disease requires a robust culture system that consistently and reliably generates large numbers of immature erythroblasts that can be induced to differentiate synchronously.
Emile van den Akker   +4 more
doaj   +1 more source

No Mitoses in Basophilic Erythroblasts

open access: yesExperimental Biology and Medicine, 1974
SummaryIn the rabbit, under conditions in which mitoses accumulated in the acidophilic erythroblasts, none were observed in the basophilic erythroblasts. On the basis of certain assumptions, the basophilic erythroblasts were divided into two size classes: of average long diameters (as measured here) 10.3 and 8.4 nm.
H, Borsook, S, Jiggins
openaire   +2 more sources

Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology

open access: yesMethods and Protocols, 2020
During erythropoiesis, the molecular chaperone alpha-hemoglobin-stabilizing protein (AHSP) sequesters free alpha-hemoglobin (αHb) and prevents precipitation of excess αHb.
Julia Walczak   +2 more
doaj   +1 more source

Ultrastructural characteristics of erythroid cells in congenital dyserythropoietic anemia type II, with a focus on peripheral cisternae and double membranes

open access: yesBlood Science, 2023
Peripheral cisternae and double membranes (PCDMs) in erythroid cells are a landmark of type II congenital dyserythropoietic anemia (CDA). To gain further insights into the mechanism of dyserythropoiesis, erythroblasts and erythrocytes in bone marrow were
Yong-Xin Ru   +3 more
doaj   +1 more source

CD8+ T cell activation by murine erythroblasts infected with malaria parasites [PDF]

open access: yes, 2013
Recent studies show that some human malaria parasite species Plasmodium falciparum and P. vivax parasitize erythroblasts; however, the biological and clinical significance of this is unclear. To investigate further, we generated a rodent malaria parasite
Imai, Takashi   +8 more
core   +1 more source

Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium

open access: yesnpj Regenerative Medicine, 2023
Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies.
Soo-Been Jeon   +9 more
doaj   +1 more source

Comprehensive Characterization and Global Transcriptome Analysis of Human Fetal Liver Terminal Erythropoiesis

open access: yesGenomics, Proteomics & Bioinformatics, 2023
The fetal liver (FL) is the key erythropoietic organ during fetal development, but knowledge on human FL erythropoiesis is very limited. In this study, we sorted primary erythroblasts from FL cells and performed RNA sequencing (RNA-seq) analyses.
Yongshuai Han   +8 more
doaj   +1 more source

THE METABOLISM OF HUMAN ERYTHROBLASTS [PDF]

open access: yesJournal of Clinical Investigation, 1936
The metabolism of human nucleated red blood cells has not previously been determined because of difficulties in procuring material. In most anemias the number of nucleated erythrocytes in the blood is so small in relation to the number of non-nucleated erythrocytes that the metabolism of the former is obscured by that of the latter.
openaire   +2 more sources

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