Results 21 to 30 of about 23,516 (234)

Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts

open access: yesFrontiers in Genetics, 2020
Erythropoiesis of human hematopoietic stem cells (HSCs) maintains generation of red blood cells throughout life. However, little is known how human erythropoiesis is regulated by long non-coding RNAs (lncRNAs). By using ChIRP-seq, we report here that the
Waritta Sawaengdee   +6 more
doaj   +1 more source

Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics

open access: yesCell Reports, 2021
Summary: Metabolic support was long considered to be the only developmental function of hematopoiesis, a view that is gradually changing. Here, we disclose a mechanism triggered during neurulation that programs brain development by donation of ...
Şükran Özsoy   +5 more
doaj   +1 more source

Fetal erythroblasts in maternal blood in relation to gestational age

open access: yes, 2003
OBJECTIVES: To determine the distribution of fetal erythroblasts in the maternal circulation at different gestations. MATERIALS AND METHODS: Maternal blood was obtained from 152 normal singleton pregnancies at 11-40 weeks of gestation.
Nicolaides, K H   +3 more
core   +5 more sources

Generation of ‘designer erythroblasts’ lacking one or more blood group systems from CRISPR/Cas9 gene‐edited human‐induced pluripotent stem cells

open access: yesJournal of Cellular and Molecular Medicine, 2021
Despite the recent advancements in transfusion medicine, red blood cell (RBC) alloimmunization remains a challenge for multiparous women and chronically transfused patients.
P. Pandey   +4 more
semanticscholar   +1 more source

Estimating biological reference intervals for cell blood counts in a dog population

open access: yesRevista Colombiana de Ciencias Pecuarias, 2020
Background: The results from automated equipment and peripheral blood smears allow correlating clinical data with cellular blood counts (CBC), generating information on pathologies of hematological and non-hematological origin in dogs.
Valentina Ochoa-Ruíz   +6 more
doaj   +1 more source

Wdr26 regulates nuclear condensation in developing erythroblasts.

open access: yesBlood, 2020
Mammalian red blood cells lack nuclei. The molecular mechanisms underlying erythroblast nuclear condensation and enucleation, however, remain poorly understood.
Ru Zhen   +8 more
semanticscholar   +1 more source

Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis.

open access: yesBlood, 2020
Plasmodium falciparum gametocytes, the sexual stages responsible for malaria parasites transmission from humans to mosquitoes, are key targets for malaria elimination.
Gaelle Neveu   +20 more
semanticscholar   +1 more source

Study of phenotypic and cytotoxic properties of erythroid cells of the spleen under hematopoiesis-stimulating effects

open access: yesМедицинская иммунология, 2023
In recent years, research has revealed a wide variety of erythroid cell functions, including modulation of innate and adaptive immune responses. Anemic or hypoxic stress stimulates a physiological response in the form of stress erythropoiesis, aimed at ...
Yu. A. Shevchenko   +2 more
doaj   +1 more source

Purification of erythroblastic nests [PDF]

open access: yesBlood, 1981
We describe a method for preparing purified erythroblastic nests in large numbers (approximately 10(6)/run) in three steps: (1) induction of splenic erythropoiesis in mice, (2) preparative differential centrifugation for the removal of erythrocytes and single cells from spleen cell suspensions, and (3) sedimentation in an isokinetic gradient of Ficoll ...
A J, Macario   +3 more
openaire   +3 more sources

Antitumor properties of nuclear erythroid cells

open access: yesСибирский онкологический журнал, 2022
Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor cells of various origins. Material and Methods. C57Bl/6 mice and P815, L1210, B16 and L929 tumor cells were used.
V. A. Kozlov   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy