Results 11 to 20 of about 13,873 (221)
Enucleation of human erythroblasts involves non-muscle myosin IIB
Blood, 2012 Mammalian erythroblasts undergo enucleation, a process thought to be similar to cytokinesis. Although an assemblage of actin, non-muscle myosin II, and several other proteins is crucial for proper cytokinesis, the role of non-muscle myosin II in ...
Kumi Ubukawa +2 more
exaly +2 more sources
British Journal of Haematology, 2000 We report a patient with autoimmune haemolytic anaemia (AIHA) with reticulocytopenia, who showed excessive apoptosis of erythroblasts. Ultrastructural analysis of bone marrow cells showed that 50% of erythroblasts had characteristic features of apoptosis,
A A Van De Loosdrecht +2 more
exaly +3 more sources
Fetal erythroblasts in maternal blood in relation to gestational age
Journal of Maternal-Fetal and Neonatal Medicine, 2003 OBJECTIVES: To determine the distribution of fetal erythroblasts in the maternal circulation at different gestations. MATERIALS AND METHODS: Maternal blood was obtained from 152 normal singleton pregnancies at 11-40 weeks of gestation.
R Al-Mufti, H Hambley, K H Nicolaides
exaly +1 more source
Parvovirus Infection Causing Aplastic Anaemia in an Immunocompetent Patient Diagnosed by Bone Marrow Aspiration Cytology [PDF]
National Journal of Laboratory Medicine, 2021 Human Parvovirus infection is associated with transient aplastic crisis as a most common complication in chronic haemolytic anaemia patients. Very few case reports are available regarding aplastic crisis in immunocompetent patients. Here the authors are
Ranjana Giri, Urmila Senapati
doaj +1 more source
Erythroblast Enucleation [PDF]
Stem Cells International, 2011 Even though the production of orthochromatic erythroblasts can be scaled up to fulfill clinical requirements, enucleation remains one of the critical rate-limiting steps in the production of transfusable red blood cells. Mammalian erythrocytes extrude their nucleus prior to entering circulation, likely to impart flexibility and improve the ability to ...
Ganesan Keerthivasan +2 more
openaire +4 more sources
Environmental Nanoparticles Reach Human Fetal Brains
Biomedicines, 2022 Anthropogenic ultrafine particulate matter (UFPM) and industrial and natural nanoparticles (NPs) are ubiquitous. Normal term, preeclamptic, and postconceptional weeks(PCW) 8–15 human placentas and brains from polluted Mexican cities were analyzed by TEM ...
Lilian Calderón-Garcidueñas +10 more
doaj +1 more source
This is not an erythroblast [PDF]
Blood, 2015 ![Figure][1] An 82-year-old woman was admitted for diffuse bone pain and deep asthenia. She was receiving erythropoietin for a refractory cytopenia with ring sideroblasts and thrombocytosis diagnosed 14 years before.
Adriana, Plesa, Pierre, Sujobert
openaire +2 more sources
MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera
Scientific Reports, 2021 Polycythaemia vera (PV) is a haematological disorder caused by an overproduction of erythroid cells. To date, the molecular mechanisms involved in the disease pathogenesis are still ambiguous.
Chartsiam Tipgomut +9 more
doaj +1 more source
Frontiers in Genetics, 2020 Erythropoiesis of human hematopoietic stem cells (HSCs) maintains generation of red blood cells throughout life. However, little is known how human erythropoiesis is regulated by long non-coding RNAs (lncRNAs). By using ChIRP-seq, we report here that the
Waritta Sawaengdee +6 more
doaj +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source