Results 41 to 50 of about 308,854 (312)

Rethinking Wh-island Effects in Chinese

open access: yes, 2022
The traditional observation that Chinese wh-arguments do not exhibit wh-island effects may be only apparent. With new evidence from “how-many” phrases, it is demonstrated that Chinese has wh-island effects even with wh-arguments.
Yang, Barry C.-Y.;Hsu, Ting-ting Christina;Kikushima, Kazunori
core   +1 more source

An experimental investigation of wh-dependencies in four island types in Romanian

open access: yesGlossa
This paper gauges the acceptability of wh-extraction from four island types in Romanian, an understudied language in this respect. Linguistic theories predict wh-dependencies to be unacceptable when the gap is located inside adjuncts, complex NPs ...
Gert-Jan Thomas Schoenmakers   +1 more
doaj   +2 more sources

Comparing Island Effects for Different Dependency Types in Norwegian

open access: yesLanguages, 2022
Recent research suggests that island effects may vary as a function of dependency type, potentially challenging accounts that treat island effects as reflecting uniform constraints on all filler-gap dependency formation.
Anastasia Kobzeva   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

How a Simple Increase in the Number of Items Can Enhance the Reliability of Linguistic Judgments: The Case of Island Experiments

open access: yesLanguages
Replication is an important aspect of experimental research and it is therefore crucial that participant-level measures (e.g., judgment scores) are reliable.
Gert-Jan Thomas Schoenmakers
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Anthropogenic Disturbances Influenced the Island Effect on Both Taxonomic and Phylogenetic Diversity on Subtropical Islands, Pingtan, China

open access: yesPlants
The investigation of taxonomic diversity within island plant communities stands as a central focus in the field of island biogeography. Phylogenetic diversity is crucial for unraveling the evolutionary history, ecological functions, and species ...
Bo Chen   +12 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Unravelling the association between polycentric urban development and landscape sustainability in urbanizing island cities

open access: yesEcological Indicators, 2022
Polycentric urban development has become popular worldwide as expected to generate greater agglomeration externality and facilitate socioeconomic achievements.
Yi Pan   +4 more
doaj   +1 more source

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