Results 51 to 60 of about 308,854 (312)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Effects of SO2 on respiratory system of adult Miyakejima resident 2 years after returning to the island.

, 2009
BACKGROUND: Mt. Oyama in Miyakejima Island erupted in June, 2000. All Miyake villagers were forced to evacuate from the island in September, 2000, due to continuous eruptions and emissions of unsafe amounts of volcanic gas, mainly SO2.
Ishigami, Ai, Makiko Nakano, Ai Ishigami, Kikuchi, Yuriko, Mitsuru Adachi, Kouichi Maruyama, Nakano, Makiko, Tazuru Tsuboi, Nishiwaki, Yuji, Morikawa, Akihiro, Yuriko Kikuchi, Takebayashi, Toru, Hiroshi Nakashima, Shoji Kudo, Yuji Nishiwaki, Michikawa, Takehiro, Adachi, Mitsuru, Kazuyuki Omae, Tanaka, Shigeru, Satoko Iwasawa, Akihiro Morikawa, Shigeru Tanaka, Takamoto Uemura, Nakashima, Hiroshi, Iwasawa, Satoko, Iwao Uchiyama, Maruyama, Kouichi, Toru Takebayashi, Kudo, Shoji, Tsuboi, Tazuru, Takehiro Michikawa, Uemura, Takamoto, Omae, Kazuyuki, Uchiyama, Iwao   +33 more
core   +1 more source

A framework for disentangling ecological mechanisms underlying the island species–area relationship

Frontiers of Biogeography, 2019
The relationship between an island’s size and the number of species on that island—the island species–area relationship (ISAR)—is one of the most well-known patterns in biogeography and forms the basis for understanding biodiversity loss in response to ...
Jonathan M. Chase, Leana Gooriah, Felix May, Wade A. Ryberg, Matthew S. Schuler, Dylan Craven, Tiffany M. Knight   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

On the origin of Halipeurus heraldicus on Round Island petrels: cophylogenetic relationships between petrels and their chewing lice [PDF]

, 2010
Lice phylogenetic relationships have often been used to elucidate host relationships and vice versa. In this study, we investigate the louse genus Halipeurus which parasitizes bird hosts in the families Procellariidae, Hydrobatidae and Pelecanoididae ...
Hammer, S., Palma, R.L., Hughes, J., Brown, R., Bugoni, L.   +4 more
core   +1 more source

Re‐approaching the small island effect

Journal of Biogeography, 2006
AbstractAim  To propose a new approach to the small island effect (SIE) and a simple mathematical procedure for the estimation of its upper limit. The main feature of the SIE is that below an upper size threshold an increase of species number with increase of area in small islands is not observed.Location  Species richness patterns from different taxa ...
Triantis, K.A., Vardinoyannis, K., Tsolaki, E.P., Botsaris, I., Lika, K., Mylonas, M.   +5 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Species–area relationships in the Andaman and Nicobar Islands emerge because rarer species are disproportionately favored on larger islands

Ecology and Evolution, 2020
The island species–area relationship (ISAR) describes how the number of species increases with increasing size of an island (or island‐like habitat), and is of fundamental importance in island biogeography and conservation. Here, we use a framework based
Leana D. Gooriah, Priya Davidar, Jonathan M. Chase   +2 more
doaj   +1 more source

Seasonal variation of dry and wet islands in Beijing considering urban artificial water dissipation

npj Climate and Atmospheric Science, 2021
Urbanization has resulted in dry/wet island effects in built-up areas. Compared to the limited number of observational datasets, simulations can provide data with richer spatial distribution, thereby proving to be more helpful for revealing the spatial ...
Zhuoran Luo, Jiahong Liu, Yongxiang Zhang, Jinjun Zhou, Weiwei Shao, Yingdong Yu, Ruitao Jia   +6 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source