Results 41 to 50 of about 1,966 (269)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Issues and Tensions in Island Heritage Management: A Case Study of Motuihe Island, New Zealand [PDF]
Island Studies Journal, 2010 This paper draws on a New Zealand case study, Motuihe Island, to examine the challenges of conserving cultural heritage in places renowned for natural heritage values.
David Bade
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
What the sea portends: a reconsideration of contested island tropes [PDF]
Island Studies Journal, 2013 This paper argues for a shift in the focus of island-themed scholarship away from theories of islandness toward an engagement with psychologies of island experience. The former project has become mired in intractable dilemmas.
Pete Hay
doaj +2 more sources
Island Studies JournalOn Taiwan’s offshore islands of Kinmen, the water supply infrastructure has experienced various challenges stemming from the physical and social conditions of islands.
Mei-Huan Chen
doaj +1 more source
The Rhythm of Non Places: Marooning the Embodied Self in Depthless Space [PDF]
, 2015 Taking as its starting point the spatiotemporal rhythms of landscapes of hyper-mobility and transit, this paper explores how the process of “marooning” the self in a radically placeless (and depthless) space—in this instance a motorway traffic island on ...
Roberts, Les
core +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Il discorso dell’anti-insularità e il poio maderense come sua negazione [PDF]
Diacronie. Studi di Storia Contemporanea, 2016 The Madeirans put the idea of the island as a center of the world before the smallness of geographic space: in this way they claim its anti-insularity point of view. The reality, therefore, determines its opposite.
Alberto Vieira
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source