Results 61 to 70 of about 1,151,315 (325)

Islands as legible geographies: perceiving the islandness of Kalaallit Nunaat (Greenland)

Journal of Marine and Island Cultures, 2018
Despite considerable research within the field of island studies, no consensus has yet been reached as to what it is that makes islands special. Around the world, islands and archipelagos are shaped by diverse spatialities and relationalities that make ...
Adam Grydehøj
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Islandness and remoteness as resources : evidence from the tourism performance of small remote island economies (SRIES) [PDF]

, 2011
Small remote island economies are known to face a number of economic challenges, particularly, in their trade relations. This paper investigates the impact of remoteness and islandness on tourism performance. Remote islands are found to be well‑endowed
Sufrauj, Shamnaaz
core   +1 more source

“It’ll be our own little Wales out there”: re-situating Bardsey Island for post-devolution Wales in Fflur Dafydd’s Twenty Thousand Saints [PDF]

, 2017
This article examines the ways in which Fflur Dafydd’s 2008 novel Twenty Thousand Saints negotiates notions of the island space in a post-devolution Welsh context.
Anderson, Jonathan Mark, Bohata, Kirsti, Morgan, Jeffrey, Smith, Kieron   +3 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Understanding Islandness Effects Through the Challenges of Water Infrastructure: A Case Study on the Kinmen Islands

Island Studies Journal
On Taiwan’s offshore islands of Kinmen, the water supply infrastructure has experienced various challenges stemming from the physical and social conditions of islands.
Mei-Huan Chen
doaj   +1 more source

Performance Enhancement of an Islanded Microgrid with the Support of Electrical Vehicle and STATCOM Systems [PDF]

, 2023
Omar Makram Kamel, Ahmed A. Zaki Diab, Mohamed Metwally Mahmoud, Ameena Saad Al‐Sumaiti, Hamdy M. Sultan   +4 more
openalex   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta, Stefano Callegaro, Antonio Canosa, Umberto Manera, Maurizio Grassano, Francesca Palumbo, Sara Cabras, Enrico Matteoni, Francesca Di Pede, Filippo De Mattei, Salvatore Tafaro, Neil M. Thakur, Ryan Grosenick, Fabiola De Marchi, Letizia Mazzini, Cristina Moglia, Andrea Calvo, Kuldip D. Dave, Adriano Chiò   +18 more
wiley   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Malapportionment as a Factor Associated With Islandness: Three Archipelagos Compared

Island Studies Journal
This study examines the relationship between malapportionment and islandness in three European archipelagos (Canary Islands, Balearic Islands, Azores), employing a comparative analysis of electoral systems.
Miguel Carranza Guasch
doaj   +1 more source