Results 141 to 150 of about 6,756 (199)

International autotransplantation of Langerhans islets into the portal tract after total pancreatectomy in a patient with chronic hereditary pancreatitis – case report and review of current literature

Gastroenterology & hepatology, 2023
Summary: Chronic pancreatitis with repeated painful relapses is a severe multifactorial, fibroinflammatory syndrome that significantly affects the quality of life of patients, mainly in terms of pain, development of diabetes mellitus, and repeated ...
Daniel Bolek, Lenka Nosáková, Miroslav Pindura, Patrik Horan, P. Bánovčin, B. Palkóci, P. Girman, J. Kříž, Lenka Németová, I. Leontovyc, K. Bittenglová, D. Osinová, J. Miklušica   +12 more
semanticscholar   +1 more source

Suppression, Stress, and Accommodation of Transplanted Islets of Langerhans [PDF]

Diabetes, 1985
Successful intrasplenic islet autotransplantation in dogs requires an islet cell mass considerably greater than what might be expected based on studies of subtotal pancreatectomy. Grafts of marginal function ultimately fail, suggesting severe limitations in the capacity of an islet graft to adapt.
Ronald C. Merrell, Francesco M. Marincola, Luther F. Cobb, Giacomo Basadonna, Masamitsu Maeda   +4 more
openaire   +2 more sources

TRANSPLANTATION OF ISLETS OF LANGERHANS FROM PILOCARPINE-PRETREATED RATS A METHOD OF ENHANCING ISLET YIELD

Transplantation, 1979
Vrbova H, Howell Sl, Margaret Tyhurst, Theodorou Na   +3 more
openaire   +4 more sources

Culture of the islets of Langerhans for transplantation

The Japanese Journal of Surgery, 1982
The isolated islets of Langerhans are the most available donors for transplantation. As the preservation of the isolated islets is difficult, we attempted to keep these tissues viable by use of an organ culture. Islets of Langerhans from adult Wistar rats were isolated by a collagenase technique and cultured in air-CO2 (95-5%) incubator at 37 degrees C.
Itsuo Miyazaki, Yasuhiko Kojima, Gizo Nakagawara   +2 more
openaire   +3 more sources

Multiple Transplantations of Islets of Langerhans

European Surgical Research, 1977
In 6 diabetic rats about 1,000 isolated islets of Langerhans were transplanted into the liver with little effect on the uninsulinism and hyperglycemia. Subsequently, a second transplantation resulted in a decrease of blood sugar to normal and in a reversal of the loss in body weight. Finally, in animals who had reversed to diabetes again, a third islet
Pichlmayr, Löhlein D, Rumpf Kd
openaire   +3 more sources

Angiogenesis and Hemodynamics of Microvasculature of Transplanted Islets of Langerhans

Diabetes, 1989
Transplantation of isolated islets of Langerhans is frequently followed by early loss of islet function. Because whether this is caused by insufficient vascularization or graft rejection is unknown, angiogenesis and microvascularization of islet grafts were studied in vivo by means of intravital microscopy.
Michael D. Menger, Konrad Messmer, F. Hammersen, Gernot Feifel, Sabine Jaeger, Paul Walter   +5 more
openaire   +3 more sources

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

Diabetes, 1999
The remarkable difference in success rates between clinical pancreas transplantation and islet transplantation is poorly understood. Despite the same histocompatibility barrier and similar immunosuppressive treatments in both transplantation procedures ...
W. Bennet, B. Sundberg, C. Groth, M. Brendel, D. Brandhorst, H. Brandhorst, R. Bretzel, G. Elgue, R. Larsson, B. Nilsson, O. Korsgren   +10 more
semanticscholar   +1 more source

Transplantation of islets of Langerhans

Journal of Hepato-Biliary-Pancreatic Surgery, 1994
The present study attempts to evaluate the possibility of using cryopreserved pancreatic islets in rats. Insulin-releasing activity was studied for the purpose of clarifying the function of cryopreserved islets. Cryopreserved pancreatic islets were also transplanted into the portal veins of recipient rats.
openaire   +2 more sources

Bovine Islets of Langerhans: Potential Source for Transplantation?

Diabetes, 1989
Two methods are described for large-scale isolation of islets from the bovine pancreas. With the single-endpoint technique the average number of islets isolated from a 73.3-g pancreas sample was 150,560, representing an estimated total islet volume of 0.391 ml. Pancreases processed by the continuous digestion-filtration method yielded an average of 246,
Bernhard J. Hering, Dietmar Romann, Milivoj Slijepcevic, Mathias D. Brendel, Konrad Federlin, Reinhard G. Bretzel, Astrid Clarius   +6 more
openaire   +3 more sources

Exocrine contamination of isolated islets of Langerhans deteriorates the process of revascularization after free transplantation.

Transplantation, 2000
BACKGROUND We investigated the influence of exocrine tissue contamination on the process of vascularization of isolated pancreatic islets of Langerhans after free transplantation into Syrian golden hamsters.
M. Heuser, B. Wolf, B. Vollmar, M. Menger   +3 more
semanticscholar   +1 more source