Results 201 to 210 of about 12,558 (256)

Transplantation of islets of Langerhans in diabetic rats.

Acta physiologica latino americana, 1978
In the present work, homogeneous isolated pancreatic islet-cells were transplanted to diabetic rats with the aim of verifying if the transplanted tissue could survive and reduce the plasma glucose concentration on the alloxan-induced diabetic receptors. For the isolation of the pancreatic islets, pancreas was incubated in collagenase solution for about
A C, Boschero, C E, Negreiros de Paiva
openaire   +1 more source

[Coagulation activation with intraportal islets of Langerhans transplantation in swine].

Annales de Chirurgie, 2001
A. Lamblin, A. Tournoys, V. Gmyr, M. Jourdain, J. Lefebvre, J. Kerr-Conte, C. Proye, F. Pattou   +7 more
semanticscholar   +1 more source

Islet transplantation. The connection of experiment and clinic exemplified by the transplantation of islets of Langerhans.

Experimental and clinical endocrinology, 1994
Since approximately 25 years islet transplantation as a mean for the treatment of diabetes has been developed from early attempts in rodents to first clinical applications in man in recent years. The review describes the results obtained in diabetic rats including metabolic effects as well as prevention of late complications.
openaire   +2 more sources

Effects of fluid dynamic stress on fracturing of cell-aggregated tissue during purification for islets of Langerhans transplantation

, 2008
H. Shintaku, T. Okitsu, Satoyuki Kawano, S. Matsumoto, Takaaki Suzuki, I. Kanno, H. Kotera   +6 more
semanticscholar   +1 more source

[Transplantation of islets of Langerhans: procedure, indications and challenges].

Nederlands tijdschrift voor geneeskunde, 2018
Pancreatic islet isolation and transplantation are complicated procedures, indicated for a carefully selected group of patients. After isolation from the pancreas, the islets are infused into the portal vein. Allogeneic islet transplantation is performed in patients with diabetes mellitus, who suffer from severe hypoglycaemic events and/or progressive ...
M F, Nijhoff, V A L, Huurman, J, Dubbeld, A R, van Erkel, T A, Rabelink, M A, Engelse, E J P, de Koning   +6 more
openaire   +1 more source

Engineering islets from stem cells for advanced therapies of diabetes

Nature Reviews Drug Discovery, 2021
Matthias Meier, Heiko Lickert
exaly  

Transplantation and in vitro perifusion of rat islets of Langerhans after slow cooling and warming in the presence of either glycerol or dimethyl sulfoxide.

Cryobiology, 1983
M. Taylor, T. Duffy, C. Hunt, S. Morgan, P. J. Davisson   +4 more
semanticscholar   +1 more source

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Nature Medicine, 2022
Yuanyuan Du, Shu-Sen Wang, Soon Yi Liew
exaly  

[Islets of langerhans and pancreas transplantation tomorrow].

Diabete & metabolisme, 1995
Pancreatic tissue grafting as a substitution for insulin deficiency of diabetes is by far the most physiological therapeutic approach of the disease. Both islets and pancreatic gland have been successfully implanted in experimental animal diabetes and in patients, resulting in full normalisation of glucose homeostasis and, in animals, prevention of ...
openaire   +1 more source

Transplantation of islets of Langerhans in diabetic rhesus monkeys.

Surgery, 1975
Islets of Langerhans from unrelated donor rhesus monkeys were transplanted into the portal vein of five rhesus monkeys which had been made diabetic by partial pancreatectomy and Streptozotocin. There was definite improvement of the diabetic state with an increase in the mean KT1/2 from 0.71 to 1.52 percent per minute. The islets were isolated by a more
D W, Scharp, J J, Murphy, W T, Newton, W F, Ballinger, P E, Lacy   +4 more
openaire   +1 more source