Results 41 to 50 of about 319,802 (176)

Clinical evaluation of the CrossNN DNA methylation classifier for central nervous system tumors

Brain Pathology, EarlyView.
CrossNN demonstrated non‐inferiority to the Heidelberg CNS Tumor Methylation Classifier. A dual‐classifier approach increased the number of clinically informative classifications with correct tumor type assignment while maintaining a low rate of incorrect predictions.
Jonas Dahnoun, Léon C. van Kempen, Senada Koljenović, Ken Op de Beeck, Tomas Menovsky, Bart Feyen, Melek Ahmed, Anne Sieben, Karen Zwaenepoel   +8 more
wiley   +1 more source

Lean-Agile Adaptations in Clinical Laboratory Accredited ISO 15189

Applied Sciences, 2015
It’s introduced Lean techniques in a Clinical Laboratory to improve the operability and the efficiency in continuous processes of analysis, failsafe systems, analysis of areas of value pursuit of zero defects and reduction of waste, and it promote ...
Carlos Vilaplana Pérez, Gloria Soria Guerrero, Federico Garriga Garzón, Angel Salas Garcia   +3 more
doaj   +1 more source

Once upon a time: a tale of ISO 15189 accreditation

Clinical Chemistry and Laboratory Medicine (CCLM), 2015
There is no doubting that healthcare professionals gave the initial impetus for establishing hospital and laboratory accreditation systems, the main purpose of which is to improve quality and patient safety, as highlighted by eminent physicians, such as Ernest Amory Codman and Avedis Donabedian [1].
PLEBANI, MARIO, SCIACOVELLI, LAURA, CHIOZZA, MARIA LAURA, PANTEGHINI, MAURO   +3 more
openaire   +2 more sources

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber, Roemer B. Brandt, Mariël Leon Morales‐Grooters, Ronald van der Wal, Sjoerd A. A. van den Berg, Jelle J. Goeman, Antoinette Maassen van den Brink, Rolf Fronczek   +7 more
wiley   +1 more source

Different Analytical Modes on Automatic Hematology Analyzers for Testing Quality Control Materials and Commutability Assessment

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Hematological disorders, critical for diagnosis, and monitoring, rely on accurate complete blood count results from automated analyzers, the reliability of which depends on robust quality control (QC). However, the ability of commutability of commercial hematology QC materials (HQCM) to behave like patient samples across different
Bingshuang Ren, Ya Cheng, Hongping Ba, Weijia Cheng, Xuwei Zhou, Hui Zhen, Shimin Wu, Jie Gong   +7 more
wiley   +1 more source

Performance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality Controls

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction It is recommended to detect lupus anticoagulant (LA) using two phospholipid‐dependent clotting assays, including a LA‐sensitive activated partial‐thromboplastin‐time (aPTT). Among these reagents, Staclot‐LA assay is performed on a mixture of test and normal plasma with and without hexagonal phase phospholipids.
V. Siguret, G. Jourdi, S. Melicine, L. Goubeau, Q. Pomorski, B. Joly‐Laffargue, A. Stepanian, M. Delrue, C. Bon, P. Meijer, E. Curis   +10 more
wiley   +1 more source

Importancia de la aplicación de las normas ISO 15189 en los laboratorios clínicos [PDF]

 Legal precept 15189 of the International Organization for Standardization is the one that is used in clinical laboratories to obtain the accreditation of the laboratories, since this accreditation is what supports the reliability of the activities ...
Azua-Menéndez, Marieta, Bravo-Chichande, Valeria Priscila, Chancay-Pincay, Gissella Janeth   +2 more
core   +1 more source

The SLMTA programme: Transforming the laboratory landscape in developing countries

African Journal of Laboratory Medicine, 2014
Background: Efficient and reliable laboratory services are essential to effective and well-functioning health systems. Laboratory managers play a critical role in ensuring the quality and timeliness of these services.
Katy Yao, Talkmore Maruta, Elizabeth T. Luman, John N. Nkengasong   +3 more
doaj   +3 more sources

Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide

The Journal of Pathology, Volume 270, Issue 3, Page 328-341, November 2026.
Abstract The implementation of digital pathology (DP) has been reported across academic, public, and private laboratory settings, providing valuable insights into workflow transformation. However, comparatively little guidance exists on how DP systems should be evaluated prior to acquisition and deployment.
Diana Montezuma, Vincenzo L'Imperio, David Ameisen, Rita Carvalho, Peter Boor, Sara P Oliveira, Nadieh Khalili, Inti Zlobec, Norman Zerbe, Jordi Temprana‐Salvador   +9 more
wiley   +1 more source

Influence of Intravenous Norepinephrine Administration on Melatonin Plasma Concentration in Awake and Anaesthetised Healthy Adult Volunteers

Journal of Pineal Research, Volume 78, Issue 6, November 2026.
ABSTRACT Melatonin (MEL) is an endogenous hormone that regulates circadian rhythm, immune function and oxidative stress responses. Norepinephrine (NE), an endogenous catecholamine, increases blood pressure through the sympathetic nervous system and is commonly administered intraoperatively or in the clinically ill patient for hemodynamic support ...
Marko MIrza Sahinovic, Ilonka Nadia de Keijzer, Manon Stern, Karin Marianne Vermeulen, Michel Maria Roger Fernand Struys, Anthony Ray Absalom, Johannes Pieter van den Berg, Jaap Jan Vos   +7 more
wiley   +1 more source