Results 21 to 30 of about 3,008 (152)

An overview of medical diagnostic laboratories in South Africa that meet the international standard of accreditation: ISO 15189

The Journal of Medical Laboratory Science and Technology of South Africa, 2021
Accreditation is an official recognition that a facility or laboratory is competent to perform specific tasks and has a documented manual on a Quality Management System (QMS) in place. According to the Accreditation Act 19 of 2006, South African National Accreditation Systems (SANAS) is the only internationally recognised accreditation body in South ...
H Khadambi-Morokane, K Bhowan, S Ayuk
openaire   +2 more sources

Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide

The Journal of Pathology, EarlyView.
Abstract The implementation of digital pathology (DP) has been reported across academic, public, and private laboratory settings, providing valuable insights into workflow transformation. However, comparatively little guidance exists on how DP systems should be evaluated prior to acquisition and deployment.
Diana Montezuma, Vincenzo L'Imperio, David Ameisen, Rita Carvalho, Peter Boor, Sara P Oliveira, Nadieh Khalili, Inti Zlobec, Norman Zerbe, Jordi Temprana‐Salvador   +9 more
wiley   +1 more source

ISO 15189 accreditation: enhancing laboratory performance, safety, and personnel competence

Journal of Laboratory Medicine
ISO 15189 accreditation provides a structured framework to ensure quality and reliability in clinical laboratories. Evidence from multiple international settings demonstrates that implementing ISO 15189–based quality management systems (QMS) can ...
Takahashi Shinichiro
doaj   +1 more source

Metrology in an ISO 15189 accredited medical biology laboratory

International Journal of Metrology and Quality Engineering, 2014
All French medical biology laboratories must be accredited according to ISO 15189 for all tests conducted. Metrology is therefore critical and covers a wide variety of areas.
Guichet C., Pellegrinelli S.
doaj   +1 more source

Bone progression in multiple myeloma: Benefit of zoledronic acid for patients achieving at least Very Good Partial Response and prognostic value of bone turnover markers

British Journal of Haematology, EarlyView.
Summary The Magnolia study demonstrated that continuation of zoledronic acid (ZOL) beyond 2 years reduces the risk of progressive bone disease (PBD) in patients with multiple myeloma (MM). This follow‐up study investigated the effects of ZOL in patients achieving very good partial response (VGPR) compared to patients who did not and whether bone ...
Michael Tveden Gundesen, Annette Juul Vangsted, Carsten Helleberg, Einar Haukås, Trine Silkjær, Jonna Skov Madsen, Jon Thor Asmussen, Elena Manuela Teodorescu, Bo Amdi Jensen, Tobias Schmidt Slørdahl, Aneta Alexandra Nielsen, Dorte Aalund Olsen, Kent Søe, Hareth Nahi, Anders Waage, Niels Abildgaard, Fredrik Schjesvold, Thomas Lund   +17 more
wiley   +1 more source

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber, Roemer B. Brandt, Mariël Leon Morales‐Grooters, Ronald van der Wal, Sjoerd A. A. van den Berg, Jelle J. Goeman, Antoinette Maassen van den Brink, Rolf Fronczek   +7 more
wiley   +1 more source

Status of development and implementation of medical laboratories accreditation in Serbia [PDF]

Journal of Medical Biochemistry, 2008
Through the release of the SRPS ISO 15189:2008 standard entitled "Medicinske laboratorije: posebni zahtevi za kvalitet i kompetentnost" conditions have been created for medical laboratory accreditation in Serbia.
Gligić Ljubinka
doaj  

Different Analytical Modes on Automatic Hematology Analyzers for Testing Quality Control Materials and Commutability Assessment

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Hematological disorders, critical for diagnosis, and monitoring, rely on accurate complete blood count results from automated analyzers, the reliability of which depends on robust quality control (QC). However, the ability of commutability of commercial hematology QC materials (HQCM) to behave like patient samples across different
Bingshuang Ren, Ya Cheng, Hongping Ba, Weijia Cheng, Xuwei Zhou, Hui Zhen, Shimin Wu, Jie Gong   +7 more
wiley   +1 more source

Effects of Fecal Sampling on Preanalytical and Analytical Phases in Quantitative Fecal Immunochemical Tests for Hemoglobin

The International Journal of Biological Markers, 2017
Background Information on preanalytical variability is mandatory to bring laboratories up to ISO 15189 requirements. Fecal sampling is greatly affected by lack of harmonization in laboratory medicine.
Stefano Rapi, Margherita Berardi, Filippo Cellai, Samuele Ciattini, Laura Chelazzi, Agostino Ognibene, Tiziana Rubeca   +6 more
doaj   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 673-683, September 2026.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source