Results 31 to 40 of about 3,008 (152)

Implementation of Quality Management System in Iranian Medical Laboratories [PDF]

Iranian Journal of Public Health, 2009
Reference health Laboratory of Iran (RHL) has been established under the Secretary of Health in 2007. This organization has been developed from integration of Reference laboratories of Iran, Directorate of General Affairs and Laboratory de­partment of ...
P Dahim , N Safadel , F Rashed Marandi, K Khodaverdian, M Rahnamaye Farzami   +4 more
doaj   +1 more source

Clinical requirements for extracellular vesicle assays

Journal of Extracellular Vesicles, 2019
The scientific and clinical interest in extracellular vesicles (EV) has grown exponentially during the past 15 years. As most research indicates that EVs can be utilised in diagnostics, prognostics and therapeutics, we may be on the brink of establishing
Lisa Ayers, Ryan Pink, David Raul Francisco Carter, Rienk Nieuwland   +3 more
doaj   +1 more source

Limited Utility of a Test‐Yolk Buffer Semen Extender for Preserving Human Semen Parameters for Use in a Diagnostic Setting

Andrology, Volume 14, Issue 6, Page 1701-1711, September 2026.
ABSTRACT Background Identification of a preservation medium that accurately retains semen parameters would be advantageous for men requiring semen analysis by allowing them to produce sperm samples at home rather than on site or even facilitate ‘mail order’ semen analysis.
Alessia Schadwell, Andrew Dawkins, Tina Holton, Olivia Whiting, Peter J. I. Ellis, Sheryl T. Homa   +5 more
wiley   +1 more source

LABORATORY DIAGNOSTICS OF CURRENT INFECTIOUS DISEASES ACCORDING TO INTERNATIONAL STANDARDS

Archives of Veterinary Medicine, 2010
One of the greatest challenges of modern laboratory diagnostic is selection of methods and procedures for fast and reliable diagnostic. Contemporary laboratory diagnostic is faced with the request to develop the technologies for rapid detection of agents
Sava Lazić, Tamaš Petrović, Maja Velhner, Dubravka Milanov, Sara Savić, Branka Vidić   +5 more
doaj   +1 more source

Mutational Signature‐Based Biomarker for Phase II Trial of Olaparib Maintenance in Advanced High‐Grade Ovarian Cancer

Cancer Science, Volume 117, Issue 8, Page 2259-2273, August 2026.
A whole‐exome sequencing–based mutational signature biomarker (MSBM) identified an HRD‐enriched population in advanced ovarian cancer. In a phase II trial, olaparib maintenance suggested clinically meaningful PFS benefit without bevacizumab, supporting MSBM as a complementary HRD assessment approach.
Katsutoshi Oda, Daisuke Shintani, Akira Nishijima, Mayuyo Mori, Kazuyoshi Kato, Shoji Nagao, Noriomi Matsumura, Masahiro Kagabu, Masataka Takenaka, Kosuke Yoshihara, Yosuke Konno, Junzo Hamanishi, Sho Sato, Shiro Takamatsu, Keiko Ueda, Kosuke Kashiwabara, Takashi Aoki, Kunihiro Nishimura, Kenji Tatsuno, Hiroyuki Aburatani, Kosei Hasegawa   +20 more
wiley   +1 more source

Reproducible Data Analysis With R in Laboratory Hematology

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 757-764, August 2026.
ABSTRACT Laboratory hematology generates large, complex datasets that increasingly exceed the capabilities of traditional spreadsheet‐based analytical workflows. Despite their familiarity, spreadsheets obscure analytical logic, encourage manual data manipulation, and lack durable records of analytical steps, limiting transparency, auditability, and ...
Amrom E. Obstfeld
wiley   +1 more source

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 1957-1976, July 2026.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Method validation of a set of 12 GEM® Premier™ 4000 blood gas analyzers for point-of-care testing in a university teaching hospital

Practical Laboratory Medicine, 2018
Background: Blood gas analyzers are often integrated into point-of-care testing provisions. International standards (ISO 22870 and 15189) as adapted to French COFRAC regulations make accreditation of point-of-care testing obligatory.
Charlotte Oris, Yoan Clavel, Matthieu Jabaudon, Annick Pialat, Hadj Abdelkader Mohamed, Frédérique Lioret, Vincent Sapin, Damien Bouvier   +7 more
doaj   +1 more source

Assessment of Liver and Kidney Safety of Silver Fir (Abies alba) Branch Extract: An Open‐Label Human Study of a Dietary Supplement

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study evaluated the short‐term effects of a standardized silver fir (Abies alba) branch extract (SFBE, Belinal) on biochemical markers of liver and kidney function in healthy adults. No statistically significant or clinically meaningful changes in hepatic or renal biomarkers were observed after 14 days of supplementation with 900 mg/day SFBE ...
Katja Schoss, Samo Kreft
wiley   +1 more source

Validation and verification of examination procedures in medical laboratories: opinion of the EFLM Working Group Accreditation and ISO/CEN standards (WG-A/ISO) on dealing with ISO 15189:2012 demands for method verification and validation [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2019
Abstract This paper reflects the opinion of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group Accreditation and ISO/CEN standards (WG-A/ISO). It aims to provide guidance for drawing up local/national documents about validation and verification of laboratory methods.
Roelofsen-de Beer, Roseri, Wielders, Jos, Boursier, Guilaine, Vodnik, Tatjana, Vanstapel, Florent, Huisman, Willem, Vukasović, Ines, Vaubourdolle, Michel, Sönmez, Çiğdem, Linko, Solveig, Brugnoni, Duilio, Kroupis, Christos, Lohmander, Maria, Šprongl, Luděk, Bernabeu- Andreu, Francisco, Meško Brguljan, Pika, Thelen, Marc   +17 more
openaire   +8 more sources