Results 41 to 50 of about 2,771 (190)

Modulation of tumor growth by crossreacting isoantibodies

Biomedicine & Pharmacotherapy, 2002
Tumor cells transfected with strong antigenic epitopes were able to stimulate humoral response against relevant wild-type tumors. Crossreacting immune sera have been obtained by immunizing C57BL/6 mice with OVA-transfected leukemia EL-4 (subclone E.G7) and OVA-transfected melanoma B16 (subclone MO.5) stimulated with interferon-gamma.
P Nguyen, Van Binh, Y S, Lone, H Thien, Duc   +2 more
openaire   +2 more sources

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Early exposure, enduring consequences: How do I manage Rh immunoglobulin prophylaxis after Rh‐mismatched transfusions in children?

Transfusion, EarlyView.
Abstract Background RhD mismatched transfusions in RhD negative women have the potential to impact future pregnancies through alloimmunization and development of hemolytic disease of the fetus and newborn (HDFN). As use of RhD positive emergency‐release blood products in pediatric trauma has increased, it has become clear that a significant ...
Kirea Lange, Alexander Bowers, Niruktha Raghavan, Hannah Borland, Leslie Greebon, Christine Leeper, Barbara Gaines, Donald Jenkins   +7 more
wiley   +1 more source

The incidence of ABO, Kell and Rh system blood groups in general population of Qazvin, Iran [PDF]

, 2019
    Introduction:ABO antigens and the glycoproteins constituting the blood groups such as Kell and Rh systems are the mostly focused blood groups in transfusion medicine.
Ahmadi, Mohammad Hossein, Azad, Mehdi, Kelki, Hoora, Maali, Amirhosein, Maroufi, Faezeh, Moradi, Fatemeh, Zolghadri, Narges   +6 more
core   +2 more sources

Routine transfusion of Rh(D)‐positive RBCs to Rh(D)‐negative patients designated as do not resuscitate conserves Rh(D)‐negative red blood cell inventory

Transfusion, EarlyView.
Abstract Background A minority of blood donors are Rh(D)‐negative, and Rh(D)‐negative red blood cell (RBC) products are often overutilized. As such, Rh(D)‐negative RBCs may be difficult to maintain in blood bank inventory. Study Design and Methods We changed our blood bank laboratory policy to approve non‐alloimmunized Rh(D)‐negative patients to ...
Julie Katz Karp, Jovanna Everetts, Juliana Guarente, Angelica Vivero, Tiffany Bohr, Mary Harach   +5 more
wiley   +1 more source

The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]

, 1995
In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G, Klein, S, Kriegsfeld, Lance, Nelson, R   +3 more
core   +1 more source

Differential complement activation by alloantibodies in sickle cell hyperhaemolysis syndrome may influence disease course

British Journal of Haematology, EarlyView.
Mamie M. Thant, Jahnavi Gollamudi, Stefanie W. Benoit, Satheesh Chonat, Jose A. Cancelas   +4 more
wiley   +1 more source

Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine

Transfusion, EarlyView.
Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena, Hyun Hyung An, Randall W. Veliquette, Edmund Carvalho, Sambit Dalui, Kaoru Takasaki, Eric Wafula, Deborah L. French, Giulia Pavani, Stella T. Chou   +9 more
wiley   +1 more source

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

Transfusion, EarlyView.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza, Thamy Silva, Mateus Domentino, Marina Conrado, João Oliveira, Elyse Moritz, Akemi Chiba, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Langhi Dante, Carla Dinardo   +11 more
wiley   +1 more source

International multicentre evaluation of a new anti‐idiotypic anti‐daratumumab for resolving pre‐transfusion interferences

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Daratumumab, a therapeutic human anti‐CD38 monoclonal antibody, improves multiple myeloma outcomes but interferes with pre‐transfusion testing by binding CD38 on reagent red blood cells (RBCs), potentially masking clinically significant alloantibodies.
Arnaud Reggiani, Sofia Lejon Crottet, Sophie Waldvogel, Charlotte Engström, Serelina Coluzzi, Antonella Matteocci, Janis R. Hamilton, Levent Tufan Kumas, Karen M. K. de Vooght, Jill R. Storry, Jennylyn Flores, Núria Nogués, Carlos Cotorruelo, Molly Rutherford, Eveline B. Nilsen, Monika Pelc‐Kłopotowska, Jolanta Korzeniowska, Alessandra Baffa, Inna Sareneva, Nor Hafizah Ahmad, Katarzyna Szczudlo, Athif Rahman, Laser Sanal, Lise Jørgensen, Karolina Majewska Rochowiak, Monika Salwierz, Elisaveta Grancharova, Bojana Zivkovic, Jessica Alvarez, Mareike Riedl, Achim Knappik   +30 more
wiley   +1 more source