Results 31 to 40 of about 2,771 (190)

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup   +4 more
wiley   +1 more source

Study of the possibility of immunological rejection of embryos as a cause of reproductive failure [PDF]

open access: yes, 1969
Call number: LD2668 .T4 1969 M44Master of ...
Merker, Jerry W.
core  

Rare “P-null” Phenotype – Two Case Reports from Western India

open access: yesGlobal Journal of Transfusion Medicine
The null phenotype in the P1PK blood group, known as “p,” is extremely rare in the world. Such individuals lack the three high-incidence antigens P, P1, and Pk.
Drashti Gajera   +5 more
doaj   +1 more source

TNF‑α Gene Polymorphisms as Determinants of Alloantibody Emergence in Hemophilia: A Systematic Review and Meta‐Analysis

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor‐alpha (TNF‐α) is a key pro‐inflammatory cytokine, and its genetic variants have been implicated in immune‐related conditions.
Alessandra Faustino da Conceição Bezerra   +3 more
wiley   +1 more source

Successful treatment of COVID‐19‐related acute respiratory distress syndrome with a rare blood type: A case report [PDF]

open access: yes, 2021
Extracorporeal membrane oxygenation is indispensable for critically severe COVID-19 patients. However, it would be inapplicable to patients with a rare blood type or blood transfusion refusal. In that case, severely conservative fluid management with the
Date, Hiroshi   +13 more
core   +1 more source

Glomerular plasmalemma vesicle‐associated protein‐1 as an endothelial remodelling marker complementing C4d in chronic active antibody‐mediated rejection

open access: yesHistopathology, EarlyView.
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi   +7 more
wiley   +1 more source

What is the best approach to blood transfusion in sickle cell disease? A scientometric analysis and literature review

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping ...
Christiane Ruffato Carminati   +6 more
wiley   +1 more source

A retrospective analysis of the antigen‐negative red blood cell supply conducted at a single centre in China

open access: yesTransfusion Medicine, EarlyView.
Abstract Objective This study aimed to analyse the distribution and demand patterns of antigen‐negative red blood cells (RBCs) in Shandong Province, China (2022–2024), with a focus on ABO blood groups and clinically significant antigens. The research was designed to provide rigorous data for advancing precision transfusion protocols and to establish a ...
Aiping Zhao   +7 more
wiley   +1 more source

Clinical and immunological studies in thrombocytopenia [PDF]

open access: yes, 1979
In this thesis some of the problems concerning etiology and diagnosis of thrombocytopenia are studied. Special attention is paid to the detection of platelet antibodies and their significance in Werlhof's disease. ...
Veenhoven, Willem Adriaan
core   +4 more sources

Clinical implications of imlifidase interference in antibody screening and transfusion management

open access: yesTransfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani   +2 more
wiley   +1 more source

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