A Case of Neonatal Neutropenia Due to Anti-Fc Gamma Receptor IIIb Isoantibodies Treated with Recombinant Human Granulocyte Colony Stimulating Factor [PDF]
Case Reports in Medicine, 2009 Alloimmunization to granulocyte-specific antigens can occur during pregnancy. Maternal antibodies of IgG class can cross the placenta to result in alloimmune neonatal neutropenia.
Maja Tomicic +4 more
doaj +2 more sources
HematologyObjectives: HLA Class I, HPA (Human platelet antigen), CD36 allo/isoantibodies, and platelet glycoprotein autoantibodies are the primary causes of immune-mediated platelet transfusion refractoriness (iPTR).
Bing Zhang +7 more
doaj +2 more sources
Modulation of tumor growth by crossreacting isoantibodies
Biomedicine & Pharmacotherapy, 2002 Tumor cells transfected with strong antigenic epitopes were able to stimulate humoral response against relevant wild-type tumors. Crossreacting immune sera have been obtained by immunizing C57BL/6 mice with OVA-transfected leukemia EL-4 (subclone E.G7) and OVA-transfected melanoma B16 (subclone MO.5) stimulated with interferon-gamma.
P Nguyen, Van Binh +2 more
openaire +3 more sources
Cytotoxic Isoantibodies and Immunologic Enhancement in Mice.
Experimental Biology and Medicine, 1966 Summary1. Cytotoxic isoantibodies and hemagglutinins are stimulated in response to H-2 isoantigenic differences between graft and host in mice. 2. This study offers data correlating cytotoxic isoantibody and immunological enhancement. 3. The mechanism of immunological enhancement has been shown to be associated with peripheral as well as central ...
Cruse, J M
core +4 more sources
In vitro characterization of rare anti-αIIbβ3 isoantibodies produced by patients with Glanzmann thrombasthenia that severely block fibrinogen binding and generate procoagulant platelets via complement activation. [PDF]
Res Pract Thromb HaemostGlanzmann thrombasthenia (GT) is a rare bleeding disorder caused by inherited defects of the platelet αβ integrin. Platelet transfusions can be followed by an immune response that can block integrin function by interfering with fibrinogen binding.
Lee CSM +7 more
europepmc +2 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Neonatal immune neutropenia due to isoantibodies against the granulocyte receptor FcγRIIIb
, 2021 Introduction: neonatal neutropenia is often secondary to sepsis, low birth weight, pregnancy-induced maternal hypertension, and other conditions. Case report: we report a case of asymptomatic isoimmune neutropenia in a pair of preterm twins.
Rodríguez-Sevilla, Juan José +5 more
core +1 more source
Perioperative Management of Emergency Off-pump Coronary Artery Bypass Grafting in a Patient with Pan-reactive Red Blood Cell Alloantibodies: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchRed Blood Cell (RBC) alloimmunisation poses critical challenges in cardiac surgery, particularly during emergency Coronary Artery Bypass Grafting (CABG), due to the risks of haemolytic reactions and incompatible transfusions. This case report details the
Kiran Muthu Rajah +4 more
doaj +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2013 OBJECTIVE: To evaluate the usefulness of DNA methods to provide a means to precisely genotypically match donor blood units for the antigen-negative type of 35 sickle cell disease ...
Daiane Cobianchi da Costa +5 more
doaj +3 more sources
Isoantibody Specificity in Post-transfusion Purpura [PDF]
Blood, 1973 Abstract Antiplatelet antibody in the serum of a fatal case of post-transfusion purpura showed specificity for the PlA1 platelet isoantigen in that the antibody was adsorbed by all PlA1-positive platelets tested but not by PlA1-negative platelets.
J P, Gockerman, N R, Shulman
openaire +2 more sources