Results 111 to 120 of about 57,189 (285)

Energetics of the Citric Acid Cycle in the Deep Biosphere

open access: yesGeophysical Monograph Series, Page 303-327., 2020

This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.

Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions

Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley  

+1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

open access: yesPest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa   +16 more
wiley   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Gut Microbiota of Gray Snub‐Nosed Monkeys: Adaptation to Seasonal Variations Through Energy Compensation and Thermogenesis

open access: yesIntegrative Zoology, EarlyView.
Based on metagenome‐assembled genomes (MAGs), the gut microbiota of the gray snub‐nosed monkeys recovered 1229 non‐redundant MAGs. The gut microbiota showed an enhanced capacity to produce energy substrates with increased conversion activity of these substrates during winter.
Yue Sun   +17 more
wiley   +1 more source

Spray-Dried Engineered Escherichia coli Whole-Cell Biocatalysts Enable Cell Recycling and In Vivo α-Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture. [PDF]

open access: yesBiotechnol Bioeng
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Jahanian A   +4 more
europepmc   +2 more sources

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

THE SYNTHESIS OF ISOCITRIC ACID

open access: yesJournal of Biological Chemistry, 1946
G W, PUCHER, H B, VICKERY
openaire   +2 more sources

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

open access: yesBritish Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne   +28 more
wiley   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

open access: yesBrain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios   +18 more
wiley   +1 more source

Studies of the phosphorylation of Escherichia coli isocitrate dehydrogenase. Recognition of the enzyme by isocitrate dehydrogenase kinase/phosphatase and effects of phosphorylation on its structure and properties

open access: yes, 1989
Escherichia coli isocitrate dehydrogenase is completely inactivated by phosphorylation of a single serine residue per subunit. We have examined the conformations of the active and phosphorylated forms of the enzyme using circular dichroism spectroscopy ...
McKee, Jillian S.   +2 more
core   +1 more source

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