Results 151 to 160 of about 57,189 (285)

Expression Of the Idh1 R132h Protein in Hepatopancreatobiliary Malignancies in A Single Center Population: Immunohistochemical Study. [PDF]

Iran J Pathol
Sweed D, Abdelbary AH, Fayed Y, Senbawy MSE, Sweed E, Elhamed SMA.   +5 more
europepmc   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, Volume 48, Issue 10, Page 2810-2820, October 2026.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

<i>Mycobacterium tuberculosis</i> partitions the Krebs cycle under iron starvation. [PDF]

Elife
Serafini A, Garza-Garcia A, Sorze D, de Carvalho LPS, Manganelli R.   +4 more
europepmc   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Right Frontal Isocitrate Dehydrogenase (IDH)-Mutant WHO Grade 3 Oligodendroglioma Presenting With Morning Headache and Gait Imbalance. [PDF]

Cureus
Metwaly L.
europepmc   +1 more source

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Spin‐ and‐gradient‐echo DSC MRI at 7 T allows for characterization of the microvasculature at an improved resolution and a reduced gadolinium‐based contrast agent dosage while maintaining increased vascular contrast. Ratios between normal‐appearing gray matter and white matter for relative cerebral blood volume and vessel size estimates were similar ...
Karen N. van der Werff, Daniëlle van Dorth, Krishnapriya Venugopal, Esther A. H. Warnert, Dirk H. J. Poot, Frans M. Vos, Marion Smits, Stefan Klein, C. Chad Quarles, Juan A. Hernandez‐Tamames, Johan A. F. Koekkoek, Jeroen de Bresser, Matthias J. P. van Osch   +12 more
wiley   +1 more source

Homology Modeling and Pharmacophore Based Inhibitor Design Targeting Isocitrate Lyase of Madurella mycetomatis-A Novel Approach Against Eumycetoma. [PDF]

Chem Biodivers
Giri S, Hazra S, Chakraborty A, Sarkar A, Adhikari T.   +4 more
europepmc   +1 more source

Pitfalls in 2HG Detection With TE-Optimized MRS at 3T. [PDF]

J Neuroimaging
ABSTRACT Background and Purpose In vivo MRS of 2‐hydroxyglutarate (2HG) may provide diagnostic and monitoring biomarkers in isocitrate dehydrogenase (IDH)‐mutated glioma. A previous meta‐analysis has shown good diagnostic accuracy of TE‐optimized PRESS for IDH‐mutated glioma, but most studies feature IDH‐wildtype glioma as a comparison.
Alcicek S, Simicic D, Blair L, Saint-Germain M, Zöllner HJ, Davies-Jenkins CW, Holdhoff M, Laterra J, Bettegowda C, Schreck KC, Lin DD, Barker PB, Kamson DO, Oeltzschner G.   +13 more
europepmc   +2 more sources

Functional analysis and clinical significance of the isocitrate dehydrogenase 2 gene in papillary thyroid carcinoma

, 2019
Jun Zhang,1–4 Linfei Hu,2–5 Huijuan Wang,2–5 Jingtai Zhi,2–5 Xiukun Hou,2–5 Yu Wu,6 Xiangqian Zheng,2–5 Ming Gao2–51Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin ...
Zhi J, Zheng X, Gao M, Zhang J, Hu L, Wang H, Hou X, Wu Y   +7 more
core