The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín +11 more
wiley +1 more source
Glucose Hypometabolic Pattern and Prediction of Isocitrate Dehydrogenase Status in Non-Contrast-Enhanced Glioma Using Z-Score-Based <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography. [PDF]
Cancers (Basel)Imai N +12 more
europepmc +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
Advanced Science, Volume 13, Issue 52, 18 September 2026.ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Molecular features of intratumoral hemorrhage in glioblastoma isocitrate dehydrogenase-wildtype. [PDF]
J NeurooncolBueno A +12 more
europepmc +1 more source
Brain and Behavior, Volume 16, Issue 9, September 2026.Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi +13 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 9, September 2026.ABSTRACT Objective Protein O‐fucosyltransferase 1 (POFUT1) has been implicated in several malignancies, but its functional and prognostic significance in glioma remains insufficiently defined. This study evaluated whether POFUT1 expression is associated with glioma progression, patient outcome, and PI3K/AKT pathway activity.
Kai Yang +8 more
wiley +1 more source
Cracking the Code of Cardiac ATP-Dependent Citrate Lyase With Wet and Dry Tools. [PDF]
CirculationWalker MA, Tian R.
europepmc +1 more source
Study of Adaptive Radiotherapy for High‐Grade Glioma Based on Interfraction MRI
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Background Currently, there is no clear guidance on the appropriate population or timing for adaptive radiotherapy (ART) in high‐grade glioma (HGG) patients. This study aims to provide individualized ART for HGG patients. Methods Participants received standard “radiotherapy combined with temozolomide” and underwent MRI before radiotherapy (FX0)
Shuangshuang He +12 more
wiley +1 more source
Oxalate synthesis pathways that contribute to oxalate accumulation in leaves of bitter dock (<i>Rumex obtusifolius</i> L.) differ between day and night. [PDF]
Plant Biotechnol (Tokyo)Sakuma W, Murayama H, Miyagi A.
europepmc +1 more source
Synthesis, Characterization, and Biological Assessment of 2‐Methoxynicotinonitrile Derivatives
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.We report the synthesis of new 2‐methoxy‐3‐cyanopyridine derivatives via the nucleophilic aromatic substitution pathway, along with their crystal structure determination and preliminary biological evaluation. The new synthetic conversion described here demonstrates a practical method of preparing structurally diverse 2‐methoxy‐3‐cyanopyridines and ...
Eman Sulaiman +6 more
wiley +1 more source