Results 211 to 220 of about 68,056 (282)

Real‐World Data From a Molecular Tumor Board‐Assisted Cancer Care From a Single Center in The Czech Republic: Is Precision Oncology an Accessible Option, or a Privilege for a Minority of Patients?

Cancer Medicine, Volume 14, Issue 15, August 2025.
This study presents a real‐world analysis of patients with advanced solid tumors discussed at the Molecular Tumor Board (MTB) of University Hospital Brno, Czech Republic, between 2021 and 2025. Comprehensive genomic profiling guided matched therapies in 17.4% of cases, with a clinical benefit (PFS2/PFS1 ≥ 1.3) observed in 41.4% of evaluable patients ...
Michal Eid, Markéta Bednaříková, Jakub Vlažný, Jitka Hausnerová, Renata Taslerová, Sára Vilmanová, Martina Jelínková, Alena Homolová, Martin Gryc, Jakub Trizuljak, Zdeněk Pavlovský, Štěpán Tuček, Dagmar Brančíková, Monika Bratová, Tomáš Rohan, Zdeněk Kala, Zdeněk Král, Jiří Mayer, Adam Svobodník, Ondřej Slabý   +19 more
wiley   +1 more source

Isocitrate dehydrogenase 1 gene mutations: a case review unveiling its biological impact on disease progression, prognosis and treatment in Chilean patients. [PDF]

BJR Case Rep
de Mayo Glasser T, García-Bloj B, Godoy JA, Sigler Chávez F, Retamal IN, Gómez-Valenzuela F, Silva I, Muñoz-Medel M, Sánchez C, Pinto F, Aravena P, Corvalán I, Erpel JM, Manque PA, Garrido M.   +14 more
europepmc   +1 more source

TRAINING INCREASES ISOCITRATE DEHYDROGENASE AND MITOCHONDRIAL TRANSHYDROGENASE IN RAT SKELETAL MUSCLE

, 1995
Richard A. Howlett, Wayne T. Willis
openalex   +1 more source

Studies on the Mechanism of Action of Isocitric Dehydrogenase

Journal of Biological Chemistry, 1960
openaire   +3 more sources

A Unique Case of Gallstone Ileus in a Patient With Crohn's Disease: Stone Impaction in an Ileal Adenocarcinoma

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Gallstone ileus represents an uncommon etiology of mechanical intestinal obstruction. Individuals with Crohn's disease are predisposed to both increased gallstone formation and a heightened risk of gastrointestinal malignancy. This case highlights the necessity of excluding malignancy when evaluating newly developed strictures in this patient ...
Tommaso Antenucci, Rosario Arena
wiley   +1 more source

Isocitrate dehydrogenase 2 mutation promotes cytarabine resistance in acute myeloid leukemia by Warburg effect. [PDF]

Hematol Oncol
Yang J, Wang Z, Wu K, Nie B, Li L, Ruan J, Zhou Q, Zeng Y, Shi M.   +8 more
europepmc   +1 more source

DOES THE CITRATE CYCLE ENZYME NAD-LINKED ISOCITRATE DEHYDROGENASE PLAY A ROLE IN RESPIRATORY CONTROL?

, 1995
Matthew R. Jackman, Wayne T. Willis
openalex   +1 more source

Gut Microbiota‐Associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High‐Altitude

Exploration, Volume 5, Issue 4, August 2025.
Long‐term migration to high‐altitude areas can readily result in chronic high‐altitude diseases; however, effective prevention and treatment methods are currently lacking. This study employed a multi‐omics approach, integrating metagenomics and metabolomics, to discover and validate that the decreased abundance of Veillonella rogosae, Streptococcus ...
Yongqiang Zhou, Zhexin Ni, Jingjing Liu, Dezhi Sun, Pan Shen, Xi Chen, Gaofu Li, Zhijie Bai, Yangyi Hu, Ningning Wang, Rui Wang, Lina Guan, Yihao Wang, Xianglin Tang, Yungang Lu, Baokun He, Haitao Lu, Wei Zhou, Yue Gao   +18 more
wiley   +1 more source

Single-cell transcriptomics reveals IRF7 regulation of the tumor microenvironment in isocitrate dehydrogenase wild-type glioma. [PDF]

MedComm (2020)
Li J, Long S, Yang Z, Wei W, Yu S, Liu Q, Hui X, Li X, Wang Y.   +8 more
europepmc   +1 more source

Polyphenol‐Based Nutritional Strategies Combined With Exercise for Brain Function and Glioma Control: Focus on Epigenetic Modifications, Cognitive Function, Learning and Memory Processes

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
The integration of polyphenol‐based nutritional strategies with structured exercise interventions presents a promising approach to control glioma progression. By targeting neuroinflammation and cellular plasticity, this combination offers a powerful dual‐targeting strategy.
Guobiao Yang, Wanying Yang, Farzam Kiarasi   +2 more
wiley   +1 more source