Results 211 to 220 of about 358,941 (349)

Supplementary materials from Tissue 2-Hydroxyglutarate as a Biomarker for <i>Isocitrate Dehydrogenase</i> Mutations in Gliomas

, 2023
Hao‐Wen Sim, Romina Nejad, Wenjiang Zhang, Farshad Nassiri, Warren Mason, Kenneth D. Aldape, Gelareh Zadeh, Eric X. Chen   +7 more
openalex   +1 more source

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas

Journal of Clinical Investigation, 2017
Gary Kohanbash, Diego A. Carrera, S. Shrivastav, Brian J. Ahn, Naznin Jahan, T. Mazor, Zinal S Chheda, Kira M. Downey, P. Watchmaker, Casey Beppler, R. Warta, N. Amankulor, C. Herold‐Mende, J. Costello, H. Okada   +14 more
semanticscholar   +1 more source

MMP14‐Dependent Activation of TGF‐β Signaling Enhances Malignancies via Promoting Necroptosis in Glioblastoma

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
MMP14 amplifies TGF‐β signaling to create a necroptosis‐heterogeneous landscape that fuels GBM progression. Targeting this axis may disrupt the adaptive mechanisms underlying treatment failure, offering a path to precision therapy for this intractable malignancy.
Haoyu Zhou, Wei Wu, Yiyang Cao, Beichen Zhang, Mingjing Zhou, Yichang Wang, Maode Wang, Jia Wang   +7 more
wiley   +1 more source

Histopathological grading affects survival in patients with isocitrate dehydrogenase-wildtype gliomas. [PDF]

Front Oncol
Hou Z, Liu D, Hou Z, Zhang H, Wang H.
europepmc   +1 more source

Anti-Apoptotic and Anti-Oxidant Proteins in Glioblastomas: Immunohistochemical Expression of Beclin and DJ-1 and Its Correlation with Prognosis. [PDF]

, 2019
Arcidiacono Biagio, Borrelli Giorgio, Cappabianca Paolo, Del Basso De Caro Marialaura, Donato Annalidia, Donato Giuseppe, Guadagno Elia, Malara Natalia, Pignatiello Sara, Presta Ivan, Solari Domenico, Somma Teresa   +11 more
core   +1 more source

Study of Isocitrate Dehydrogenase 1and 2 Mutations in Adult Egyptian Patients with Denovo Acute Myeloblastic Leukemia, Their Relation to Clinical Characteristics, FLT3/ITD and Nucleophosmin 1 Mutations and Impact on Treatment Outcome

, 2019
Sherine Samir Barakat, Manal Elsorady, Mona Wagdy Ayad, Dalia Abd Elmoety Elneely, Fatma Mohamed Abd Elfatah   +4 more
openalex   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source

Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]

, 1972
Bachmaier, B., Kiefhaber, P., Nolte, J., Pette, D., Schneider, H., Scriba, Peter Christian   +5 more
core  

P12.36.A ISOCITRATE DEHYDROGENASE INHIBITION PRIMES GLIOBLASTOMA CELLS FOR STATIN-INDUCED CELL DEATH [PDF]

Laura Marosits, Christine Pirker, Sabine Spiegl‐Kreinecker, Walter Berger   +3 more
openalex   +1 more source

Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas

Neuro-Oncology, 2017
Biqi Zhang, Ken Chang, S. Ramkissoon, S. Tanguturi, W. Bi, D. Reardon, K. Ligon, B. Alexander, P. Wen, Raymond Y Huang   +9 more
semanticscholar   +1 more source