Results 221 to 230 of about 190,806 (273)

Role of the tumor board when prescribing mutant isocitrate dehydrogenase inhibitors to patients with isocitrate dehydrogenase-mutant glioma. [PDF]

Neurooncol Pract
Roth P, Capper D, Calabrese E, Halasz LM, Jakola AS.   +4 more
europepmc   +1 more source

Improving radiomics-based isocitrate dehydrogenase 1 prediction in glioma patients using semi-supervised machine learning models. [PDF]

BMC Med Imaging
Ahmadzadeh AM, Jafarnezhad A, Elyassirad D, Vatanparast M, Gheiji B, Faghani S.   +5 more
europepmc   +1 more source

Correction to "Isocitrate Dehydrogenase 2 Mutation Promotes Cytarabine Resistance in Acute Myeloid Leukemia by Warburg Effect". [PDF]

Hematol Oncol
europepmc   +1 more source

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The isocitrate dehydrogenase from cyanobacteria

Archives of Microbiology, 1983
The present communication describes the properties of isocitrate dehydrogenase in crude extracts from the unicellular Anacystis nidulans and from heterocysts and vegetative cells of Nostoc muscorum and Anabaena cylindrica. The activity levels of this enzyme are much higher in heterocysts than in vegetative cells of N. muscorum and A.
Hermann Bothe, H Bothe
exaly   +3 more sources

The regulatory properties of isocitrate dehydrogenase kinase and isocitrate dehydrogenase phosphatase from Escherichia coli ML308 and the roles of these activities in the control of isocitrate dehydrogenase

European Journal of Biochemistry, 1984
Isocitrate dehydrogenase kinase can use ATP but not other nucleoside triphosphates as a phosphate donor. It responds hyperbolically to both ATP and isocitrate dehydrogenase. The kinase is inhibited sigmoidally by low concentrations of DL‐isocitrate and hyperbolically by ADP, AMP, NADPH, phosphoenolpyruvate and several other effectors.
G A, Nimmo, H G, Nimmo
openaire   +3 more sources

Role of isocitrate dehydrogenase in glioma

Expert Review of Neurotherapeutics, 2011
Recently, the isocitrate dehydrogenase (IDH) enzymes have become a focal point for research aimed at understanding the biology of glioma and identifying novel targets for therapy. Following the publication of a landmark genetic sequencing study in 2008, which identified IDH1 as a frequently mutated gene in glioblastoma, much work has been carried out ...
Minesh Mehta, Brian M Alexander
exaly   +3 more sources

Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation and Reductive Carboxylation in Cancer and Their Clinical Significance

Cancers, 2022
The human isocitrate dehydrogenase (IDH) gene encodes for the isoenzymes IDH1, 2, and 3, which catalyze the conversion of isocitrate and α-ketoglutarate (α-KG) and are required for normal mammalian metabolism. Isocitrate dehydrogenase 1 and 2
Zhenzhou Chen, Qiwei He
exaly   +2 more sources

The role of isocitrate in control of the phosphorylation of isocitrate dehydrogenase in Escherichia coli ML308 [PDF]

FEBS Letters, 1985
Isocitrate dehydrogenase from Escherichia coli is regulated by a reversible phosphorylation mechanism. We confirm here that this permits intracellular isocitrate to rise to a level that can sustain growth on acetate.
H G Nimmo
exaly   +2 more sources