Results 251 to 260 of about 358,941 (349)

Data from FDA Approval Summary: Ivosidenib for Relapsed or Refractory Acute Myeloid Leukemia with an Isocitrate Dehydrogenase-1 Mutation

, 2023
Kelly J. Norsworthy, Lola Luo, Vicky Hsu, Ramadevi Gudi, Sarah E. Dorff, Donna Przepiorka, Albert Deisseroth, Yuan-Li Shen, Christopher M. Sheth, Rosane Charlab, Gene M. Williams, Kirsten B. Goldberg, Ann T. Farrell, Richard Pazdur   +13 more
openalex   +1 more source

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma.

Cancer Discovery, 2016
Supriya K. Saha, J. Gordan, B. Kleinstiver, P. Vu, Mortada S. Najem, Jia-Chi Yeo, Lei Shi, Y. Kato, Rebecca S Levin, James T. Webber, Leah J. Damon, Regina K. Egan, Patricia Greninger, U. McDermott, M. Garnett, R. Jenkins, K. Rieger-Christ, T. Sullivan, A. Hezel, A. Liss, Y. Mizukami, L. Goyal, C. Ferrone, A. Zhu, J. Joung, K. Shokat, C. Benes, N. Bardeesy   +27 more
semanticscholar   +1 more source

Insights Into CEST Contrast at 2 ppm in Enhancing and Nonenhancing Lesions From Glioma Patients Scanned at 7 T

NMR in Biomedicine, Volume 38, Issue 12, December 2025.
We investigated the 7 T MRI 2 ppm CEST pool contrast in (1.) high‐grade and (2.) low‐grade gliomas, finding significant differences between enhancing and nonenhancing lesions (3A,B), and between the healthy appearing white matter and nonenhancing lesions (3C,D). The 2 ppm CEST pool suggests valuable noninvasive contrast for glioma imaging.
Bárbara Schmitz‐Abecassis, Jeroen de Bresser, Linda Dirven, Martin J.B. Taphoorn, Matthias J. P. van Osch, Johan A. F. Koekkoek, Ece Ercan, the 7 T MRI Neuro‐Oncology consortium Monique Baas‐Thijssen   +7 more
wiley   +1 more source

Isocitrate dehydrogenase-mutant astrocytoma in persons aged 55 years and older: Survival differences versus the young. [PDF]

J Neuropathol Exp Neurol
Siddiq Z, Gilani A, Ung TH, Kleinschmidt-DeMasters BK.   +3 more
europepmc   +1 more source

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma.

Neuro-Oncology, 2016
M. I. de la Fuente, R. Young, Jennifer Rubel, M. Rosenblum, J. Tisnado, S. Briggs, J. Arevalo-Perez, J. Cross, Carl Campos, K. Straley, Dongwei Zhu, Chuanhui Dong, Alissa A. Thomas, A. Omuro, C. Nolan, E. Pentsova, T. Kaley, J. Oh, R. Noeske, E. Maher, Changho Choi, P. Gutin, A. Holodny, K. Yen, L. Deangelis, I. Mellinghoff, S. Thakur   +26 more
semanticscholar   +1 more source

Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
This study explores the metabolic potential of Lentilactobacillus hilgardii for malolactic fermentation in winemaking. Genomic and in silico analyses, combined with experimental validation, reveal its resilience at low temperatures and unique enzymatic traits. Comparative insights with Oenococcus oeni highlight L.
Giacomo Mantegazza, Nicola Mangieri, Elnaz Vojoudi Yazdi, Pasquale Russo, Diego Mora, Giorgio Gargari   +5 more
wiley   +1 more source

Magnetic resonance imaging fractal analysis of O(6)-methylguanine-DNA methyltransferase promoter methylation status in isocitrate dehydrogenase wild-type glioblastoma. [PDF]

Quant Imaging Med Surg
Xue C, Wang K, Dong W, Han T, Zhou Q, Zhang P, Liang L, Wang P, Zhou J, Guan S, Liu X.   +10 more
europepmc   +1 more source

Supplementary Table S2 from Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance [PDF]

Stephen V Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, María L. Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yi-Lun Sun, Rebecca Tagett, Felipe J. Nunez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R Lowenstein, Maria G. Castro   +25 more
openalex   +1 more source

MRI detection of 2-hydroxyglutarate (2HG) to diagnosis and monitor isocitrate dehydrogenase 1 ( IDH1 )-mutant gliomal tumors [PDF]

, 2012

openalex   +1 more source

Cryptic CAM photosynthesis in Joshua tree (Yucca brevifolia, Y. jaegeriana)

New Phytologist, Volume 248, Issue 5, Page 2583-2598, December 2025.
Summary Joshua trees are long‐lived perennial monocots native to the Mojave Desert in North America. Composed of two species, Yucca brevifolia and Y. jaegeriana (Asparagaceae), Joshua trees are imperiled by climate change, with decreases in suitable habitat predicted under future climate change scenarios.
Karolina Heyduk, Sara Sciulla, Bridget Hennessy, Madeline Czymmek, Edward V. McAssey, Chase Kane, G Young Kim, Ifeoluwa Sogunle, Lulu Heublein, Dhriti Sriram, Bryan MacNeill, Michael T. Hren, Todd C. Esque, Jeremy B. Yoder, Michael R. McKain, Christopher Irwin Smith, Lesley A. DeFalco   +16 more
wiley   +1 more source