Results 21 to 30 of about 37,394 (195)

Isocitrate Lyase and Succinate Semialdehyde Dehydrogenase Mediate the Synthesis of α-Ketoglutarate in Pseudomonas fluorescens [PDF]

Frontiers in Microbiology, 2019
Glycerol is an important by-product of the biodiesel industry and its transformation into value-added products like keto acids is being actively pursued in order to improve the efficacy of this renewable energy sector.
Azhar A. Alhasawi, Sean C. Thomas, Sujeethar Tharmalingam, Sujeethar Tharmalingam, Sujeethar Tharmalingam, Sujeethar Tharmalingam, Felix Legendre, Vasu D. Appanna   +7 more
doaj   +2 more sources

Inhibitory Effects of Diketopiperazines from Marine-Derived Streptomyces puniceus on the Isocitrate Lyase of Candida albicans [PDF]

Molecules, 2019
The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase, and plays an important role in the pathogenesis of microorganisms during infection.
Heegyu Kim, Ji-Yeon Hwang, Jongheon Shin, Ki-Bong Oh   +3 more
doaj   +2 more sources

Huangqin decoction disrupts energy metabolism of Trichophyton rubrum, with isocitrate lyase as a potential target [PDF]

Scientific Reports
The dermatophyte Trichophyton rubrum (T. rubrum) is a highly specialized filamentous fungus that primarily infects keratinized tissues and is the most common pathogen isolated from human dermatophytosis.
Suqing Yang, Yican He, Youjin Ge, Baode Shen, Chengying Shen   +4 more
doaj   +2 more sources

An isocitrate lyase gene-deleted strain of Nocardia seriolae in live attenuated vaccine development against fish nocardiosis [PDF]

Frontiers in Veterinary Science
BackgroundFish nocardiosis caused by Nocardia seriolae is a severe bacterial disease in aquaculture, causing significant economic losses. The effectiveness of antibiotics in dealing with nocardiosis induced by N. seriolae is not satisfactory.
Guanying Lin, Yan Li, Suying Hou, Yiming Wen, Xiaoya Lei, Ting Huang, Yuben Chen, Jianlin Chen, Liqun Xia   +8 more
doaj   +2 more sources

In Silico Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa [PDF]

Molecules, 2018
Buruli ulcer (BU) is caused by Mycobacterium ulcerans and is predominant in both tropical and subtropical regions. The neglected debilitating disease is characterized by chronic necrotizing skin lesions attributed to a mycolactone, which is a macrolide ...
Samuel K. Kwofie, Bismark Dankwa, Emmanuel A. Odame, Francis E. Agamah, Lady P. A. Doe, Joshua Teye, Odame Agyapong, Whelton A. Miller, Lydia Mosi, Michael D. Wilson   +9 more
doaj   +2 more sources

RegA Plays a Key Role in Oxygen-Dependent Establishment of Persistence and in Isocitrate Lyase Activity, a Critical Determinant of In vivo Brucella suis Pathogenicity [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
For aerobic human pathogens, adaptation to hypoxia is a critical factor for the establishment of persistent infections, as oxygen availability is low inside the host. The two-component system RegB/A of Brucella suis plays a central role in the control of
Elias Abdou, María P. Jiménez de Bagüés, Ignacio Martínez-Abadía, Safia Ouahrani-Bettache, Véronique Pantesco, Alessandra Occhialini, Sascha Al Dahouk, Stephan Köhler, Véronique Jubier-Maurin   +8 more
doaj   +2 more sources

Suvanine Sesterterpenes from a Tropical Sponge Coscinoderma sp. Inhibit Isocitrate Lyase in the Glyoxylate Cycle [PDF]

Marine Drugs, 2014
The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase (MLS). Mutants of Candida albicans lacking ICL are markedly less virulent in mice than the wild-type.
So-Hyoung Lee, Tae Hyung Won, Heegyu Kim, Chan-Hong Ahn, Jongheon Shin, Ki-Bong Oh   +5 more
doaj   +2 more sources

Inhibition of Paracoccidioides lutzii Pb01 isocitrate lyase by the natural compound argentilactone and its semi-synthetic derivatives. [PDF]

PLoS ONE, 2014
The dimorphic fungus Paracoccidioides spp. is responsible for paracoccidioidomycosis, the most prevalent systemic mycosis in Latin America, causing serious public health problems.
Renata Silva do Prado, Ricardo Justino Alves, Cecília Maria Alves de Oliveira, Lucília Kato, Roosevelt Alves da Silva, Guilherme Oliveira Quintino, Silvio do Desterro Cunha, Célia Maria de Almeida Soares, Maristela Pereira   +8 more
doaj   +2 more sources

Integrated Bioinformatics-Based Subtractive Genomics Approach to Decipher the Therapeutic Drug Target and Its Possible Intervention against Brucellosis

Bioengineering, 2022
Brucella suis, one of the causative agents of brucellosis, is Gram-negative intracellular bacteria that may be found all over the globe and it is a significant facultative zoonotic pathogen found in livestock.
Kanwal Khan, Munirah Sulaiman Othman Alhar, Muhammad Naseer Abbas, Syed Qamar Abbas, Mohsin Kazi, Saeed Ahmad Khan, Abdul Sadiq, Syed Shams ul Hassan, Simona Bungau, Khurshid Jalal   +9 more
doaj   +1 more source

Isocitrate Lyase in Green Leaves [PDF]

Plant Physiology, 1973
Isocitrate lyase (EC 4.1.3.1) has been demonstrated in crude dialyzed extracts of healthy spinach (Spinacia oleracea) leaves from commercial sources and wheat (Triticum aestivum) and maize (Zea mays) leaves stored in darkness in the cold room for 1 week.
H R, Godavari, S S, Badour, E R, Waygood
openaire   +2 more sources