Results 141 to 150 of about 57,276 (400)
The Medicinal Chemistry of Imidazotetrazine Prodrugs [PDF]
YesTemozolomide (TMZ) is the standard first line treatment for malignant glioma, reaching “blockbuster” status in 2010, yet it remains the only drug in its class.
Moody, Catherine L.+1 more
core +2 more sources
Boron‐Based Functionalities Enhance the Potency of 2,5‐Dimethylfuran‐Based IDO1 Inhibitors
Indoleamine‐2,3‐dioxygenase‐1 (IDO1), a key immunoregulatory enzyme, is inhibited by novel boron derivatives (closo‐1,2‐ and 1,7‐carborane, boronic acids and esters, and benzoxaboroles) of 2,5‐dimethylfuran, each displaying low μM affinity for the human recombinant enzyme.
Thomas J. C. Carraro+4 more
wiley +1 more source
Iron(II)-catalyzed hydroamination of isocyanates [PDF]
A two-coordinate Fe(II) m-terphenyl complex acts as a precatalyst for the hydroamination of isocyanates, affording urea and biuret derivatives, with product selectivity accomplished via modification of the reaction conditions.
Blake, Alexander J.+6 more
core +2 more sources
Chemical upcycling of poly(ethylene terephthalate) waste: Moving to a circular model
Abstract The circular economy is a path that society, governments, and business must adopt to develop a viable and sustainable model for plastic production. Following the route guided by the United Nations and the new laws of the European Union, such as the Green Deal, it will be able to put an end to the great problem of this era, the inadequate ...
María Dolores de Dios Caputto+3 more
wiley +1 more source
The Absorption Spectra and Dissociation Energies of Cyanic Acid and Some Isocyanates [PDF]
Sho-Chow Woo, Ta-Kong Liu
openalex +1 more source
Fire toxicity - The elephant in the room? [PDF]
Fire toxicity is the largest cause of death and injury from unwanted fires, yet it is the least well studied area of fire science and engineering. Fire toxicity increases by factors up to 50, as the fire becomes under-ventilated.
Stec, Anna A
core +1 more source
Circularly Polarized Luminescence in Rotaxanes and Catenanes
This review highlights the chiral rotaxanes and catenanes possessing static or stimuli‐responsive circularly polarized luminescence (CPL) activity both in solution and in the solid state. It also discusses macromolecular and supramolecular CPL‐emissive materials derived from these mechanically interlocked molecules.
Arthur H. G. David+2 more
wiley +1 more source
New polyurethanes from oxypropylated olive stone [PDF]
The purpose of this work is to explore the possibility of chemically modifying the generated polyols (oxypropylated olive stone) through reactions with isocyanates to produce polyurethanes, other than rigid polyurethane foams.
Barbosa, Mariana Martinho+3 more
core
BACKGROUND Isocyanates remain a leading cause of work-related asthma (WRA). METHODS Two independent data systems were analyzed for the period 1993-2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states,
Daniel Lefkowitz+12 more
semanticscholar +1 more source