Results 141 to 150 of about 57,276 (400)

The Medicinal Chemistry of Imidazotetrazine Prodrugs [PDF]

open access: yes, 2014
YesTemozolomide (TMZ) is the standard first line treatment for malignant glioma, reaching “blockbuster” status in 2010, yet it remains the only drug in its class.
Moody, Catherine L.   +1 more
core   +2 more sources

Boron‐Based Functionalities Enhance the Potency of 2,5‐Dimethylfuran‐Based IDO1 Inhibitors

open access: yesChemBioChem, EarlyView.
Indoleamine‐2,3‐dioxygenase‐1 (IDO1), a key immunoregulatory enzyme, is inhibited by novel boron derivatives (closo‐1,2‐ and 1,7‐carborane, boronic acids and esters, and benzoxaboroles) of 2,5‐dimethylfuran, each displaying low μM affinity for the human recombinant enzyme.
Thomas J. C. Carraro   +4 more
wiley   +1 more source

Iron(II)-catalyzed hydroamination of isocyanates [PDF]

open access: yes, 2019
A two-coordinate Fe(II) m-terphenyl complex acts as a precatalyst for the hydroamination of isocyanates, affording urea and biuret derivatives, with product selectivity accomplished via modification of the reaction conditions.
Blake, Alexander J.   +6 more
core   +2 more sources

Chemical upcycling of poly(ethylene terephthalate) waste: Moving to a circular model

open access: yesJournal of Polymer Science, Volume 60, Issue 24, Page 3269-3283, 15 December 2022., 2022
Abstract The circular economy is a path that society, governments, and business must adopt to develop a viable and sustainable model for plastic production. Following the route guided by the United Nations and the new laws of the European Union, such as the Green Deal, it will be able to put an end to the great problem of this era, the inadequate ...
María Dolores de Dios Caputto   +3 more
wiley   +1 more source

Fire toxicity - The elephant in the room? [PDF]

open access: yes, 2017
Fire toxicity is the largest cause of death and injury from unwanted fires, yet it is the least well studied area of fire science and engineering. Fire toxicity increases by factors up to 50, as the fire becomes under-ventilated.
Stec, Anna A
core   +1 more source

Circularly Polarized Luminescence in Rotaxanes and Catenanes

open access: yesChemistryEurope, EarlyView.
This review highlights the chiral rotaxanes and catenanes possessing static or stimuli‐responsive circularly polarized luminescence (CPL) activity both in solution and in the solid state. It also discusses macromolecular and supramolecular CPL‐emissive materials derived from these mechanically interlocked molecules.
Arthur H. G. David   +2 more
wiley   +1 more source

New polyurethanes from oxypropylated olive stone [PDF]

open access: yes, 2012
The purpose of this work is to explore the possibility of chemically modifying the generated polyols (oxypropylated olive stone) through reactions with isocyanates to produce polyurethanes, other than rigid polyurethane foams.
Barbosa, Mariana Martinho   +3 more
core  

Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008.

open access: yesAmerican Journal of Industrial Medicine, 2015
BACKGROUND Isocyanates remain a leading cause of work-related asthma (WRA). METHODS Two independent data systems were analyzed for the period 1993-2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states,
Daniel Lefkowitz   +12 more
semanticscholar   +1 more source

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