Results 271 to 280 of about 67,105 (318)

A Biologically Informed Vision‐Guided Framework for Interpretable T Cell Receptor–Epitope Binding Prediction

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Integrating hierarchical physicochemical features via a bio‐inspired design, the DAISY framework robustly predicts T‐cell receptor binding, significantly outperforming state‐of‐the‐art models on unseen epitopes. It uniquely offers visual interpretability via Score‐CAM visualizations and profound clinical relevance, correlating with T‐cell expansion ...
Yajing Yuan, Junwei Chen, Yufang Zhang, Yitian Fang, Zhongcheng Fang, Yanyi Chu, Jiayi Li, Chen Zhang, Yuzhe Li, Dongqing Wei   +9 more
wiley   +1 more source

Boosting Nanofiltration Membrane Selectivity via Amine‐Polymer Additive Engineering for Efficient Lithium Extraction From Brine

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A diffusion‐controlled interfacial polymerization strategy incorporating poly(allylamine) (PAA) into piperazine (PIP) solution enables precise tuning of amine monomer diffusion and polyamide (PA) network formation with trimesoyl chloride (TMC). The resulting nanofiltration membranes exhibit crumpled morphology, appropriate surface charge, and enhanced ...
Shaofan Duan, Shuai Jiang, Ping Xu, Zhan Li, Pengfei Zhang, Yanyan Liu, Atsushi Matsuoka, Yuqing Lin, Jie Shen, Kecheng Guan, Tomohisa Yoshioka, Hideto Matsuyama   +11 more
wiley   +1 more source

Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu, Peiji Deng, Qianfan Chen, Qijun Sun, Yanhan Wang, Hongyu Shi, Kang Liang   +6 more
wiley   +1 more source

Imaged Capillary Isoelectric Focusing Coupled with Native Mass Spectrometry Combined with Other Separation Techniques for In-Depth Characterization of a Novel Cysteine-Linked Adc Disitamab Vedotin

Gang Wu, Xiaoxi Zhang, Xin Wang, Jialiang Du, Meng Li, Gangling Xu, Min Du, Chuanfei Yu   +7 more
openalex   +1 more source

Next‐generation Alzheimer's therapeutics: target assessment and enablement at the Indiana University School of Medicine–Purdue University TREAT‐AD Center

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract The incidence of Alzheimer's disease (AD) continues to increase, despite decades of effort to develop disease‐modifying therapies. In response, the National Institute on Aging (NIA) established the TaRget Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT‐AD) centers to address the gap between basic research and ...
Timothy I. Richardson, Rebecca C. Klein, Kun Huang, Jie Zhang, Andrew D. Mesecar, Jeffrey L. Dage, Brent Clayton, Bruce T. Lamb, Alan D. Palkowitz   +8 more
wiley   +1 more source

Genotype‐dependent variation in buffering capacity and pH stability of sugarcane juice during fermentation

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 1, Page 27-35, January/February 2026.
Abstract Buffering capacity (BC) is essential for maintaining pH stability during fermentation, directly impacting yeast performance, aroma formation, and final beverage quality. This study evaluated the BC and pH dynamics of sugarcane juice from 10 genotypes before and after fermentation to identify traits associated with juice stability.
Maria Clara De‐Barros, Normando Ribeiro‐Filho   +1 more
wiley   +1 more source

Antiproliferative Effect of Okra Seed Protein Isolate against HepG2 and A549 Cell Lines

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Cytotoxic effects exhibited by OSPI against A549 cells significantly reduced the cell viability. Elevated caspase levels induced by OSPI in Hep‐G2 cells suggest intrinsic and extrinsic apoptosis. Treatment with OSPI and DOF exhibited elevated p53 expression in A549 cells, suggesting p53‐mediated apoptosis.
Letisha Maistry, Abe Shegro Gerrano, John J. Mellem   +2 more
wiley   +1 more source

Development of Isoelectric Focusing Techniques for Protein Analyses

, 2008
Yanwei Zhan
openalex   +1 more source

Identification of Beta-Lactamase Enzymes by Isoelectrical Focusing Method in Acinetobacter baumannii

, 2002
Emel Yılmaz, Halis Akalın, Cüneyt Özakın, Özgül KISA, Ayhan Kubar, Suna Gedikoğlu, Okan Töre   +6 more
openalex   +1 more source

Capillary Isoelectric Focusing of Proteins with Carrier Ampholyte pH Gradient and Immobilized pH Gradient

, 2005
Min Deng
openalex   +1 more source