Results 61 to 70 of about 117,884 (290)

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

open access: yesAdvanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen   +5 more
wiley   +1 more source

A new paradigm for optimized experimental design in cIEF platforms aimed at an accurate robust and reliable mAbs charge-variant assessment

open access: yesScientific Reports
The success of therapeutic monoclonal antibodies (mAbs) and their biosimilars, highlights the challenge to control their purity, identity, and stability.
Marcello Belfiore   +4 more
doaj   +1 more source

Multi-­‐dimensional Protein Identification Technology [PDF]

open access: yes, 2016
Before the rise of the Multidimentional Protein Identification Technology (MudPIT), protein and peptide mixtures were resolved using traditional proteomic technologies like the gel-­‐ based 2D chromatography that separates proteins by isoelectric ...
Berri-Trapero, Yumana   +1 more
core  

Complexation of DNA with positive spheres: phase diagram of charge inversion and reentrant condensation

open access: yes, 2001
The phase diagram of a water solution of DNA and oppositely charged spherical macroions is studied. DNA winds around spheres to form beads-on-a-string complexes resembling the chromatin 10 nm fiber.
B. I. Shklovskii   +2 more
core   +1 more source

Functionalisation of Ti6Al4V and hydroxyapatite surfaces with combined peptides based on KKLPDA and EEEEEEEE peptides [PDF]

open access: yes, 2017
Surface modifications are usually performed on titanium alloys to improve osteo-integration and surface bioactivity. Modifications such as alkaline and acid etching, or coating with bioactive materials such as hydroxyapatite, have previously been ...
Ben-Nissan, Besim   +4 more
core   +6 more sources

Isoelectric points of multi-domain proteins [PDF]

open access: yesBioinformation, 2007
Although the distribution of protein isoelectric points is multi-modal, large proteins show isoelectric points less variable than small proteins and their isoelectric points tend to converge to a unique value, close to the pH of the milieu in which the proteins are functional, as far as the protein dimension increases.
openaire   +3 more sources

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

open access: yesAdvanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez   +4 more
wiley   +1 more source

pH dependence of charge multipole moments in proteins

open access: yes, 2017
Electrostatic interactions play a fundamental role in the structure and function of proteins. Due to ionizable amino acid residues present on the solvent-exposed surfaces of proteins, the protein charge is not constant but varies with the changes in the ...
Bozic, Anze Losdorfer, Podgornik, Rudolf
core   +1 more source

Isoelectric Point of Manganese Oxide [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1974
Abstract The isoelectric point (IEP) of manganese oxide is measured on samples prepared by heating β-MnO2 and amorphous manganese oxide, MnO1.75, at temperatures from 200 to 1400°C. The IEP values thus obtained are characteristic of each stage of the oxidation of manganese oxide; that is, <5.1 for MnO2, 7.6–9.0 for α-Mn2O3, and 3 ...
Tetsuo Morimoto, Shigeharu Kittaka
openaire   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

open access: yesAdvanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa   +14 more
wiley   +1 more source

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