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Isoenzymes in Clinical Diagnosis [PDF]
The recent literature attests to the increasing number of enzymes for which isoenzymes or subunit structure or both are known. Several symposia and reviews have been published within the past few years. 46-50 Some enzyme activities for which isoenzymes have been described are listed in table 4.
Nathan O. Kaplan, Theodore L. Goodfriend
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Radioimmunoassay of creatine kinase isoenzymes in human serum: isoenzyme MM.
Abstract Measurement of the mass concentration of serum enzymes by radioimmunoassay provides direct quantitation of specific isoenzymes and may be less subject to some of the limitations of traditional assay procedures for enzymes. We describe the development of a sensitive and specific radioimmunoassay for the muscle isoenzyme of ...
Van Steirteghem, Andre+2 more
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Creatine Phosphokinase Isoenzymes [PDF]
CREATINE phosphokinase (adenosine triphosphate: creatine phosphotransferase) has been shown by electrophoretic separation on agar gel and starch gel to exist in multiple molecular forms (isoenzymes)1–3. This communication describes a staining technique for creatine phosphokinase (CPK) and its application to the demonstration of CPK isoenzymes separated
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Adverse Drug-Drug Interaction Between Phenobarbital and Fluconazole in Two Dogs. [PDF]
ABSTRACT Phenobarbital (PB) is an antiseizure medication widely used in dogs that is metabolized by hepatic cytochrome P450 (CYP) enzymes. Fluconazole, a commonly prescribed antifungal medication, inhibits several CYP isoenzymes and can impair PB metabolism.
Jaramillo M+5 more
europepmc +2 more sources
Determination of LDH Isoenzymes
Abstract A method has been developed for the quantitation of LDH isoenzymes on cellulose acetate paper, taking advantage of the direct fluorometric procedures based on reduced nicotinamide adenine dinucleotide (NADH). The procedure is simple and the reagents relatively stable, allowing the test to become a routine procedure in clinical ...
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Novel Derivatives of 3-Amino-4-hydroxy-benzenesulfonamide: Synthesis, Binding to Carbonic Anhydrases, and Activity in Cancer Cell 2D and 3D Cultures. [PDF]
Vainauskas V+12 more
europepmc +1 more source
Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression. [PDF]
Fang T+7 more
europepmc +1 more source