Results 131 to 140 of about 91,012 (293)
Serum lactate dehydrogenase isoenzyme- 1 in children with yolk sac tumor [PDF]
H Kinumaki +5 more
openalex +1 more source
A 2‐year‐old female golden hamster presented with non‐pruritic alopecia of the hindquarters. Diagnostic imaging and cytological evaluation revealed a unilateral adrenal mass consistent with an adrenocortical tumour, while biochemical analyses suggested corticosteroid secretion.
Mathilde Firmin Billaux +6 more
wiley +1 more source
ABSTRACT Background Non‐steroidal anti‐inflammatory drugs (NSAIDs) are recommended for perioperative analgesic treatment. However, NSAID treatment may be associated with increased risk of adverse events. We investigated the risks of serious adverse events with perioperative NSAID treatment in patients undergoing orthopaedic surgery.
Shaheer Bukhari +10 more
wiley +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Liquid-chromatographic determination of isoenzymes of alkaline phosphatase in serum and tissue homogenates. [PDF]
Eckhard Schöenau +2 more
openalex +1 more source
RDH11 is a minor isoenzyme that catalyses the oxidation of 11‐cis‐retinol to 11‐cis‐retinal in the retinal pigment epithelium, alongside RDH5 and RDH10. Biallelic null variants in RDH11 lead to upregulation of RDH5 and RDH10 (transcriptional adaptation), maintaining 11‐cis‐retinal bioavailability, but still causing Retinal Pigment Epitheliopathy due to
Kirk A. J. Stephenson +11 more
wiley +1 more source
ABSTRACT Breast cancer, a malignant tumour that frightens women, ruthlessly claims the lives of tens of thousands of women around the world every year. However, the mechanism by which YTHDF3 regulates the occurrence and development of breast cancer is still imperfect.
ZiQian Liu +8 more
wiley +1 more source
Identification of germ-line chimaeras by polymerase chain reaction and isoenzyme analysis of mouse spermatozoa [PDF]
G. Bruce Mann +3 more
openalex +1 more source
Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long +3 more
wiley +1 more source
How enzyme economy shapes metabolic fluxes
Metabolic fluxes are governed by physical and economic principles. Stationarity constrains them to a subspace in flux space and thermodynamics makes them lead from higher to lower chemical potentials.
Liebermeister, Wolfram
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