Results 111 to 120 of about 45,019 (252)

Prevalence of Potentially Inappropriate Apixaban Prescribing Within a Single‐Centre Tertiary Hospital

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 2, June 2026.
ABSTRACT Objective Apixaban is widely recommended as first line therapy for atrial fibrillation (AF) and venous thromboembolism (VTE). Despite the widespread availability of dosing guidelines, anecdotal evidence suggests clinicians do not routinely follow these recommendations. Inappropriate dose reduction is associated with suboptimal patient outcomes.
Katherine J. Creeper   +5 more
wiley   +1 more source

Purification of glutamate dehydrogenase isoenzymes and characterization of their substrate specificities

open access: yes, 2003
Glutamate dehydrogenase (GDH) isoenzymes were purified from control, and ribonucleoside triphosphate (NTP)-treated peanut seedlings. GDH purification was by preparative-scale, free solution isoelectric focusing, followed by native PAGE, and the ...
Osuji, Godson O.   +6 more
core   +1 more source

Characterization of Trypanosoma rangeli Strains Isolated in Central and South America: an Overview

open access: yesMemorias do Instituto Oswaldo Cruz, 1999
Trypanosoma rangeli is a hemoflagelate parasite that infects domestic and sylvatic animals, as well as man, in Central and South America. T. rangeli has an overlapping distribution with T.
Grisard Edmundo C   +5 more
doaj  

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3565-3587, June 2026.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna   +17 more
wiley   +1 more source

Comparison of HEMOlysis Markers Among Three Pulsed Field Ablation Systems: HEMO‐PFA Study

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 6, Page 1249-1258, June 2026.
ABSTRACT Background Pulsed field ablation (PFA) has emerged as a novel non‐thermal modality for atrial fibrillation (AF) ablation. While hemolysis is a known complication of PFA, comparative data among different systems remain limited. Methods We prospectively enrolled 150 consecutive AF patients undergoing ablation with one of three PFA systems ...
Kazuhisa Matsumoto   +11 more
wiley   +1 more source

Lactic dehydrogenase isoenzymes in urinary tract infections and aminoglycoside nephrotoxicity

open access: yes, 1983
Lactic dehydrogenase isoenzymes in urinary tract infections and aminoglycoside ...
P. Rizzotti   +4 more
core  

Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a common pathophysiological process in reperfusion therapy following myocardial infarction. It exacerbates myocardial damage and negatively impacts patient prognosis. This study aims to explore potential regulatory targets and related mechanisms in MIRI.
Baoxin Tang   +4 more
wiley   +1 more source

Gastroprotective Effects of Hexanic Extract of the Leaves of Spondias purpurea and Its Underlying Mechanism of Action

open access: yesJournal of Food Process Engineering, Volume 49, Issue 6, June 2026.
Histopathological analysis of gastric mucosa stained with HE and PAS of rats submitted to induction of ulcers with acetic acid. The animals were treated orally with vehicle (injured control), ranitidine, and SpHE (25 mg/kg) for 14 days. In A and B, observe preserved mucosa and submucosal layers (black asterisk) and presence of the barrier protection of
Cynthia Layse Ferreira de Almeida   +9 more
wiley   +1 more source

Lactate dehydrogenase (LDH) isoenzymes patterns in ocular tumours

open access: yes, 1991
Estimation of lactate dehydrogenase (LDH) isoenzymes in the serum and aqueous humor was carried out in 15 cases of benign ocular tumour, 15 cases of malignant tumor and 15 normal cases.
Singh Rajendra   +3 more
core  

Porcine Liver Esterase‐Catalyzed Dynamic Kinetic Resolution of a Lactone‐Bridged Biaryl: Impact of Organic Cosolvents on Enantioselectivity

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 20, 27 May 2026.
A stereolabile lactone‐bridged biaryl enables dynamic kinetic resolution to provide a conformationally stable ring‐opened biaryl. A significant positive effect of water‐immiscible organic cosolvents on the enantioselectivity in a reaction catalyzed by porcine liver esterase has been discovered for the first time.
Neha Dhiman   +6 more
wiley   +1 more source

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