Results 51 to 60 of about 48,809 (249)
Substrate-Enzyme Interaction in Pig Liver Esterase [PDF]
Force field and first principles molecular dynamics simulations on complexes of pig liver esterase (pig liver isoenzymes and a mutant) and selected substrates (1-phenyl-1-ethyl acetate, 1- phenyl-2-butylacetate, proline-{\beta}-naphthylamide and methyl butyrate) are presented.
arxiv
Neuraminidase enzymes (NEU) play a crucial role in many physiological and pathological conditions. Humans have four isoenzymes of NEU and their specific roles continue to be investigated. Isoenzyme‐selective inhibitors are needed as research tools and may lead to future therapeutics.
Mostafa Radwan+2 more
wiley +1 more source
The cylcooxygenase isoforms COX‐1 and COX‐2 are involved in the production of prostaglandins in physiological and pathological processes. The overexpression of COX‐2 under inflammatory conditions as well as its role in cancer and neurodegenerative diseases necessitates the need to develop and improve non‐steroidal anti‐inflammatory drugs.
Lea Ueberham+8 more
wiley +1 more source
Comparison of methods for obtaining doubled haploids of carrot
Doubled haploid lines of carrot can be obtained through androgenesis in anther cultures and in isolated microspore cultures. The two methods were compared using three carrot cultivars (‘Kazan F1’, ‘Feria F1’, and ‘Narbonne F1’) at the androgenesis ...
Waldemar Kiszczak+4 more
doaj +1 more source
This work carried out to evaluates the polymorhism in the silkworm of different lineages using the isoenzymes electrophoresis to detect biochemical markers and to investigate the genetics of populations for those lineages.
Ludimilla Ronqui+2 more
doaj +1 more source
ABSTRACT Background Gastric cancer (GC) stands out as one of the most prevalent forms of malignant tumors globally, characterized by a notably high mortality rate. In spite of progress in medical science and treatment alternatives, the survival rate over 5 years continues to stay under 40%.
Yang Shaokang+5 more
wiley +1 more source
Introduction: Multilocus enzyme electrophoresis (MLEE) is the reference standard for the characterization of Leishmania species. The test is restricted to specialized laboratories due to its technical complexity, cost, and time required to obtain results.
Clemencia Ovalle-Bracho+3 more
doaj +1 more source
Recent Advancements in Microfluidic Biosensors for Clinical Applications
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley +1 more source
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma+10 more
wiley +1 more source
: To evaluate the effect of accelerated aging to overcome dormancy of hybrid Brachiaria cv. Mulato II (U. brizantha x U. decumbens x U. ruziziensis), seeds were collected from two lots with and without scarification, submitted to 42 °C and high humidity (
Diego de Sousa Pereira+4 more
doaj +1 more source