Results 121 to 130 of about 221,447 (295)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Isoflurane anesthesia and sleep deprivation trigger delayed and selective sleep alterations

Scientific Reports
Isoflurane anesthesia (IA) partially compensates NREM sleep (NREMS) and not REM sleep (REMS) requirement, eliciting post-anesthetic REMS rebound. Sleep deprivation triggers compensatory NREMS rebounds and REMS rebounds during recovery sleep as a result ...
Leesa Joyce, Clara Carrillo Mas, Veronica Meedt, Matthias Kreuzer, Gerhard Schneider, Thomas Fenzl   +5 more
doaj   +1 more source

Isoflurane-induced Facilitation of the Cardiac Sarcolemmal KATPChannel [PDF]

, 2002
Kazuhiro J. Fujimoto, Zeljko J. Bosnjak, Wai‐Meng Kwok   +2 more
openalex   +1 more source

Ion‑Mediated Structural Engineering of Hydrogel Interfaces for Tunable Mechanical and Analyte Diffusion Properties in Electrochemical Biosensors

Advanced Materials, EarlyView.
An ion‐mediated structural engineering strategy enables versatile modulation of PVA–Alginate hydrogel microstructure. We systematically examine how different ion combinations affect hydrogel mechanical properties and analyte diffusivity. Applying this novel strategy to hydrogel as the outer membrane in an electrochemical glucose biosensor allows ...
Dongwook Lee, Soo A Kim, Beom‐Jun Shim, Yurim Lee, Tae Young Kim, Sunghyun Park, Yeontaek Lee, Hyeong Gyu Choi, Kayoung Son, Su Bin Han, Keun‐Young Yook, Seo Jung Kim, Won‐Yong Lee, Jungmok Seo, Jayoung Kim   +14 more
wiley   +1 more source

Plasma Concentration and Cardiovascular Effects of Lidocaine during Continuous Epidural Administration in Dogs Anesthetized with Isoflurane

, 2010
Iwao SAKONJU, Kenichi Maeda, Koichi Karasawa, Toshiyuki TADOKORO, Tomoko Kakuta, Katsuaki TAKASE   +5 more
openalex   +2 more sources

A1219 THE EFFECT OF 1 MAC ISOFLURANE ON CEREBROVASCULAR RESPONSE TO INCREASED OR DECREASED CEREBRAL PERFUSION PRESSURE [PDF]

, 1990
Robert W. McPherson, S. A. Derrer, Richard J. Traystman   +2 more
openalex   +1 more source

3D‐Printable, Honeycomb‐Inspired Tissue‐Like Bioelectrodes for Patient‐Specific Neural Interface

Advanced Materials, EarlyView.
3D printed MRI‐compatible tissue‐like neural electrodes tailored to individual gyral patterns. This honeycomb‐inspired printable gel electrode (HiPGE) employs a bioinspired architecture with soft hydrogels, engineered to match the softness of brain tissue.
Marzia Momin, Luyi Feng, Xiaoai Chen, Salahuddin Ahmed, Basma AlMahmood, Li‐Pang Huang, Jiashu Ren, Xinyi Wang, Hyunjin Lee, Samuel R. Cramer, Nanyin Zhang, Sulin Zhang, Tao Zhou   +12 more
wiley   +1 more source

Room 224-226, 10/18/2000 10: 30 AM - 12: 00 PM (PD) Single-Channel Basis for the Effect of Isoflurane on Shaker H4 IR Potassium Channels  [PDF]

, 2000
Jichang Li, Ana M. Correa
openalex   +1 more source

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

Advanced Materials, EarlyView.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu, Qiang Long, Yihao Liu, Xiuqiao Sun, Baoding Zhang, Binxin Liao, Weibin Wu, Wangxi Hai, Pei Zhang, Wenhua Lian, Yuewen Zhu, Zheng Wang, Caisheng Wu, Xianming Deng, Hélder A. Santos, Xiaofeng Ye   +15 more
wiley   +1 more source

Biphasic Change of Progenitor Proliferation in Dentate Gyrus After Single Dose of Isoflurane in Young Adult Rats

, 2013
Nan Lin, Tiffany S. Moon, Greg Stratmann, Jeffrey W. Sall   +3 more
openalex   +1 more source