Results 131 to 140 of about 21,511 (293)
Arquivo Brasileiro de Medicina Veterinária e ZootecniaIt is important to identify the best inspired fraction of oxygen in a variety of situations, including sevoflurane or isoflurane anesthesia, in spontaneously breathing rabbits.
M. Horr +6 more
doaj +1 more source
Advanced Science, EarlyView.Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu +9 more
wiley +1 more source
Bax was upregulated by isoflurane treatment.
, 2013 (A) Left panel: An example of western blot for total Bax (indicated by 2D2 antibody) suggested that total Bax levels were increased by isoflurane in the absence or presence of eAβ1-42 peptide.
Hailiang Yan (284342) +5 more
core +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Data_Sheet_1_Ferroptosis Contributes to Isoflurane Neurotoxicity.PDF
, 2019 The underlying mechanisms of isoflurane neurotoxicity in the developing brain remain unclear. Ferroptosis is a recently characterized form of programmed cell death distinct from apoptosis or autophagy, characterized by iron-dependent reactive oxygen ...
Yimeng Xia (6187415) +3 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
Effect of isoflurane on multilamellar liposome-Analysis by 19F-NMR
, 2023 [Objectives] To investigate the interaction of a general anesthetic with biological membranes, we measured 19F nuclear magnetic resonance (NMR) spectra of isoflurane on the isoflurane-multilamellar liposome (MLV) system.
渋谷, 真希子 +4 more
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