Results 121 to 130 of about 21,511 (293)

Room 224-226, 10/18/2000 10: 30 AM - 12: 00 PM (PD) Single-Channel Basis for the Effect of Isoflurane on Shaker H4 IR Potassium Channels  [PDF]

, 2000
Jichang Li, Ana M. Correa
openalex   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Isoflurane-induced learning impairment measured by fear conditioning test.

, 2013
A: freezing behavior during training sessions for 18-month old Fisher 344 rats that were exposed to isoflurane in the presence or absence of lidocaine 27 days ago. Results are means±S.D.
Lin Cao (294505), Daowei Lin (294507), Liaoliao Li (294506), Zhiyi Zuo (294508)   +3 more
core   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Azi-isoflurane, a Photolabel Analog of the Commonly Used Inhaled General Anesthetic Isoflurane.

, 2010
Volatility and low-affinity hamper an ability to define molecular targets of the inhaled anesthetics. Photolabels have proven to be a useful approach in this regard, although none have closely mimicked contemporary drugs. We report here the synthesis and
Bhattacharji, Aditya, Dailey, William P, Xi, Jin, Eckenhoff, Roderic G, Shimaoka, Motomu, Covarrubias, Manuel   +5 more
core  

Charcoal as an airway isoflurane reflection filter

, 1998
The isoflurane-saving and CO2-retaining effects of a charcoal filter were compared with a Siemens standard heat and moisture (HME) exchanger and an emptied specimen (dummy).
Reinstrup, Peter,, Steptoe, P, Luttropp, Hans-Henrik, Dahm, S L, Reinstrup, Peter, Luttropp, Hans-Henrik,, Lund University.   +6 more
core   +1 more source

Non-thermoregulatory Shivering in Patients Recovering from Isoflurane or Desflurane Anesthesia  [PDF]

, 1998
Ernst-Peter Horn, Daniel I. Sessler, Thomas Standl, Frank Schroeder, Hans-Jürgen Bartz, Juan Carlos Beyer, Jochen Schulte am Esch   +6 more
openalex   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Induction of anaesthesia with desflurane and isoflurane in the rabbit [PDF]

, 2001
Patricia Hedenqvist, J. V. Roughan, L. Antunes, H.E Orr, Paul Flecknell   +4 more
openalex   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source