Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]
, 2015 BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR +8 more
core +1 more source
Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]
PLoS ONE, 2012 Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao +3 more
doaj +1 more source
The Effects of Changing from Isoflurane to Desflurane on the Recovery Profile during the Latter Part of Anesthesia [PDF]
, 2010 It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery.
Baek, Chong-Wha +8 more
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Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats. [PDF]
PLoS ONE, 2017 Isoflurane anesthesia has been shown to be responsible for cognitive impairment in Alzheimer's disease (AD) and development of AD in the older age groups.
Shuai Zhang +6 more
doaj +1 more source
Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia. [PDF]
, 2015 BackgroundThe effects of anesthesia on the equine electroencephalogram (EEG) after administration of various drugs for sedation, induction, and maintenance are known, but not that the effect of inhaled anesthetics alone for EEG recording.ObjectiveTo ...
Aleman, M +8 more
core +1 more source
Euthanasia of laboratory mice: Are isoflurane and sevoflurane real alternatives to carbon dioxide?
PLoS ONE, 2018 In the European Union (EU) millions of laboratory mice are used and killed for experimental and other scientific purposes each year. Although controversially discussed, the use of carbon dioxide (CO2) is still permitted for killing rodents according to ...
N. Marquardt +6 more
semanticscholar +1 more source
Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans
Scientific Reports, 2021 Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang +8 more
doaj +1 more source
Time-Dependent Effects of Anesthetic Isoflurane on Reactive Oxygen Species Levels in HEK-293 Cells [PDF]
, 2014 The inhalation anesthetic isoflurane has been reported to induce caspase activation and apoptosis, which may lead to learning and memory impairment. However, the underlying mechanisms of these effects are largely unknown.
Cheng, Baiqi +5 more
core +2 more sources
Journal of Neurophysiology, 2018 General anesthesia is ubiquitous in research and medicine, yet although the molecular mechanisms of anesthetics are well characterized, their ultimate influence on cortical electrophysiology remains unclear.
Nicholas J. Michelson, T. Kozai
semanticscholar +1 more source
Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage [PDF]
, 2014 Background: Intracerebral hemorrhage is a subtype of stroke that has a poor prognosis without an adequate therapy. Recently, the use of anesthetics such as isoflurane has been shown to be protective after cerebral ischemia.
Esposito, Elga +2 more
core +1 more source