Enhanced Fear Memory in Adult Male C57BL/6 Mice Following Low-Dose Isoflurane Exposure During Juvenile Development. [PDF]
Brain BehavSun J +9 more
europepmc +3 more sources
The Effects of Changing from Isoflurane to Desflurane on the Recovery Profile during the Latter Part of Anesthesia [PDF]
, 2010 It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery.
Baek, Chong-Wha +8 more
core +1 more source
The General Anesthetic Isoflurane Bilaterally Modulates Neuronal Excitability
iScience, 2020 Summary: Volatile anesthetics induce hyperactivity during induction while producing anesthesia at higher concentrations. They also bidirectionally modulate many neuronal functions. However, the neuronal mechanism is unclear.
Mengchan Ou +7 more
doaj +1 more source
The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]
PLoS ONE, 2013 The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou +4 more
doaj +1 more source
Ferroptosis Contributes to Isoflurane Neurotoxicity
Frontiers in Molecular Neuroscience, 2019 The underlying mechanisms of isoflurane neurotoxicity in the developing brain remain unclear. Ferroptosis is a recently characterized form of programmed cell death distinct from apoptosis or autophagy, characterized by iron-dependent reactive oxygen ...
Yimeng Xia +3 more
semanticscholar +1 more source
Neurobiology of Disease, 2013 Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li +5 more
doaj +1 more source
Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage [PDF]
, 2014 Background: Intracerebral hemorrhage is a subtype of stroke that has a poor prognosis without an adequate therapy. Recently, the use of anesthetics such as isoflurane has been shown to be protective after cerebral ischemia.
Esposito, Elga +2 more
core +1 more source
Time-Dependent Effects of Anesthetic Isoflurane on Reactive Oxygen Species Levels in HEK-293 Cells [PDF]
, 2014 The inhalation anesthetic isoflurane has been reported to induce caspase activation and apoptosis, which may lead to learning and memory impairment. However, the underlying mechanisms of these effects are largely unknown.
Cheng, Baiqi +5 more
core +2 more sources
Activation of D1 Dopamine Receptors Induces Emergence from Isoflurane General Anesthesia [PDF]
, 2012 Background: A recent study showed that methylphenidate induces emergence from isoflurane anesthesia. Methylphenidate inhibits dopamine and norepinephrine reuptake transporters.
Brown, Emery N. +3 more
core +1 more source
Euthanasia of laboratory mice: Are isoflurane and sevoflurane real alternatives to carbon dioxide?
PLoS ONE, 2018 In the European Union (EU) millions of laboratory mice are used and killed for experimental and other scientific purposes each year. Although controversially discussed, the use of carbon dioxide (CO2) is still permitted for killing rodents according to ...
N. Marquardt +6 more
semanticscholar +1 more source