Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans
Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang+8 more
doaj +1 more source
Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats. [PDF]
Postoperative cognitive dysfunction (POCD) is a clinical phenomenon characterized by cognitive deficits in patients after anesthesia and surgery, especially in geriatric surgical patients. Although it has been documented that isoflurane exposure impaired
Feijuan Kong+6 more
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USE OF INHALANT ANESTHETICS IN THREE SNAKE SPECIES [PDF]
Different snake species respond differently to various anesthetic agents. Hence, an anesthetic procedure developed for one species cannot necessarily be safely transferred to another species.
Blouin-Demers, Gabriel+4 more
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General anesthesia does not have persistent effects on attention in rodents [PDF]
Background: Studies in animals have shown that general anesthesia can cause persistent spatial memory impairment, but the influence of anesthetics on other cognitive functions is unclear.
Amanda G. Nelson+8 more
core +2 more sources
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.+2 more
core +2 more sources
Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A.+9 more
core +1 more source
Preconditioning of isoflurane on spinal cord ischemia can increase the number of inducible nitric oxide synthase-expressing motor neurons in rat [PDF]
BackgroundSpinal cord ischemia with resulting paraplegia remains one of the most common complications after repair of thoracoabdominal aortic aneurysms or dissection.
Yun-Hee Sung+6 more
doaj +1 more source
Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits? [PDF]
PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of ...
Holmes, KA, Sneyd, JR
core +1 more source
Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil. [PDF]
Although many studies have shown that isoflurane exposure impairs spatial memory in aged animals, there are no clinical treatments available to prevent this memory deficit.
Diansan Su+6 more
doaj +1 more source
Neonatal exposure to isoflurane can result in neuroapoptosis and persistent cognitive impairments. However, the underlying mechanisms remain elusive. Anaphase-promoting complex/cyclosome (APC/C) and its co-activator Cdh1 are E3 ubiquitin ligases that ...
Xuan Li+7 more
doaj +1 more source