Results 41 to 50 of about 307,909 (397)

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR, Brosnan, RJ, Fletcher, DJ, Holliday, TA, Kass, PH, LeCouteur, RA, Steffey, EP, Tharp, B, Williams, DC   +8 more
core   +1 more source

Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]

PLoS ONE, 2012
Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao, Liaoliao Li, Daowei Lin, Zhiyi Zuo   +3 more
doaj   +1 more source

Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment

Journal of Neuroinflammation, 2018
Elderly patients are more likely to suffer from postoperative cognitive dysfunction (POCD) after surgery and anesthesia. Except for declined organ function, the particular pathogenesis of POCD in elderly patients remains unknown.
Zhi Wang, Shiyu Meng, Lin Cao, Ying Chen, Zhiyi Zuo, S. Peng   +5 more
semanticscholar   +1 more source

Neuroprotective effects of miR-142-5p downregulation against isoflurane-induced neurological impairment

Diagnostic Pathology, 2020
Background Isoflurane can lead to neuron damage to the developing brain, resulting in learning and memory disability. The aim of this study was to investigate the role of miR-142-5p on isoflurane-induced neurological impairment.
Cuili Xie, Hongyue Wang, Yu Zhang, Yanhua Wei   +3 more
doaj   +1 more source

The Effects of Changing from Isoflurane to Desflurane on the Recovery Profile during the Latter Part of Anesthesia [PDF]

, 2010
It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery.
Baek, Chong-Wha, Cha, Su-Man, Jung, Yong-Hun, Kang, Hyun, Kim, Jin-Yun, Kim, Seong-Deok, Koo, Gill-Hoi, Park, Sun-Gyoo, Woo, Young-Cheol   +8 more
core   +1 more source

The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]

PLoS ONE, 2013
The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou, Ioannis Savvas, Yves P S Moens, Dimitrios Vasilakos, Dimitrios Raptopoulos   +4 more
doaj   +1 more source

The General Anesthetic Isoflurane Bilaterally Modulates Neuronal Excitability

iScience, 2020
Summary: Volatile anesthetics induce hyperactivity during induction while producing anesthesia at higher concentrations. They also bidirectionally modulate many neuronal functions. However, the neuronal mechanism is unclear.
Mengchan Ou, Wenling Zhao, Jin Liu, Peng Liang, Han Huang, Hai Yu, Tao Zhu, Cheng Zhou   +7 more
doaj   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

Neurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li, Jinbo Yin, Liaoliao Li, Jiao Deng, Chenzhuo Feng, Zhiyi Zuo   +5 more
doaj   +1 more source

Lower doses of isoflurane treatment has no beneficial effects in a rat model of intracerebral hemorrhage [PDF]

, 2014
Background: Intracerebral hemorrhage is a subtype of stroke that has a poor prognosis without an adequate therapy. Recently, the use of anesthetics such as isoflurane has been shown to be protective after cerebral ischemia.
Esposito, Elga, Lo, Eng H, Mandeville, Emiri T   +2 more
core   +1 more source

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L, Krafft, Paul R, Leitzke, Arthur S, Tang, Jiping, Van Allen, Nicole R, Zhang, John H   +5 more
core   +1 more source