Results 41 to 50 of about 317,847 (279)
Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats
Journal of Pharmacological Sciences, 2023 We compared the effects of two anesthetics, isoflurane and urethane on bladder function in rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under isovolumetric conditions, mechanosensitive single-unit afferent ...
Naoki Aizawa, Tomoe Fujita
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Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats. [PDF]
PLoS ONE, 2017 Isoflurane anesthesia has been shown to be responsible for cognitive impairment in Alzheimer's disease (AD) and development of AD in the older age groups.
Shuai Zhang +6 more
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Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization. [PDF]
PLoS ONE, 2011 Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation.
Yiying Zhang +8 more
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BJA Open, 2022 Background: Emerging data suggest that volatile anaesthetic agents may be protective during critical illness. Methods: Three-month-old Sprague Dawley rats were randomly allocated to one of four groups: isoflurane during surgery followed by 3 days of ...
Keita Ikeda +2 more
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Activation of D1 Dopamine Receptors Induces Emergence from Isoflurane General Anesthesia [PDF]
, 2012 Background: A recent study showed that methylphenidate induces emergence from isoflurane anesthesia. Methylphenidate inhibits dopamine and norepinephrine reuptake transporters.
Brown, Emery N. +3 more
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Journal of Neurophysiology, 2018 General anesthesia is ubiquitous in research and medicine, yet although the molecular mechanisms of anesthetics are well characterized, their ultimate influence on cortical electrophysiology remains unclear.
Nicholas J. Michelson, T. Kozai
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Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans
Scientific Reports, 2021 Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang +8 more
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Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats. [PDF]
PLoS ONE, 2013 Postoperative cognitive dysfunction (POCD) is a clinical phenomenon characterized by cognitive deficits in patients after anesthesia and surgery, especially in geriatric surgical patients. Although it has been documented that isoflurane exposure impaired
Feijuan Kong +6 more
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Frontiers in Physiology, 2022 Inhalation anesthetics isoflurane and sevoflurane have been widely used in clinical practice for anesthesia. However, the molecular mechanisms underlying the faster recovery from sevoflurane anesthesia than isoflurane anesthesia remain largely ...
Zongyuan Ma +4 more
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Frontiers in Cellular Neuroscience, 2018 Nod-like receptor protein 3 (NLRP3) inflammasome activation has been implicated in the pathogenesis of general anesthesia (GA)-induced neuroinflammation and cognitive impairment in aged rodents.
Yunxia Fan +6 more
semanticscholar +1 more source