Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats [PDF]
, 2016 BACKGROUND: Although emergence from general anesthesia is clinically treated as a passive process driven by the pharmacokinetics of drug clearance, agents that hasten recovery from general anesthesia may be useful for treating delayed emergence ...
Ba, Demba E +8 more
core +1 more source
Hydrogen sulfide ameliorates isoflurane-induced cognitive impairment in mice: Implication of caspase-3 activation [PDF]
, 2020 Purpose: Isoflurane could induce cognitive impairment and activate caspase-3. However, the mechanism of action is unclear and target interventions are unavailable.
Chen, Dan +7 more
core +2 more sources
Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia. [PDF]
, 2015 BackgroundThe effects of anesthesia on the equine electroencephalogram (EEG) after administration of various drugs for sedation, induction, and maintenance are known, but not that the effect of inhaled anesthetics alone for EEG recording.ObjectiveTo ...
Aleman, M +8 more
core +1 more source
Volatile anesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin αIIbβ3. [PDF]
PLoS ONE, 2013 In clinical reports, the usage of isoflurane and sevoflurane was associated with more surgical field bleeding in endoscopic sinus surgeries as compared to propofol.
Koichi Yuki +3 more
doaj +1 more source
Breakdown of local information processing may underlie isoflurane anesthesia effects [PDF]
, 2016 The disruption of coupling between brain areas has been suggested as the mechanism underlying loss of consciousness in anesthesia. This hypothesis has been tested previously by measuring the information transfer between brain areas, and by taking reduced information transfer as a proxy for decoupling.
arxiv +1 more source
Mediators of Inflammation, 2023 Postoperative cognitive dysfunction (POCD) is a well-known complication after surgery with cognitive impairments. Angiopoietin-like protein 2 (ANGPTL2) has been found to be associated with inflammation.
Xiaoyan Huang +5 more
doaj +1 more source
Isoflurane Preconditioning Promotes the Survival and Migration of Bone Marrow Stromal Cells
Cellular Physiology and Biochemistry, 2015 Background: Preconditioning with the volatile anesthetic isoflurane exerts protective effects in animal models of ischemia. The cytoprotective effects of isoflurane are dependent on the expression of hypoxia inducible factor-1 (HIF-1), a dimeric ...
Yu Sun +4 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2020 Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative
Kai Zhang +13 more
doaj +1 more source
Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. [PDF]
PLoS ONE, 2012 Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory.
Diansan Su +6 more
doaj +1 more source
Frontiers in Physiology, 2022 Inhalation anesthetics isoflurane and sevoflurane have been widely used in clinical practice for anesthesia. However, the molecular mechanisms underlying the faster recovery from sevoflurane anesthesia than isoflurane anesthesia remain largely ...
Zongyuan Ma +4 more
doaj +1 more source