FEBS Open Bio, EarlyView.Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu +9 more
wiley +1 more source
British Journal of Anaesthesia, 2016 BACKGROUND Isoflurane is one of the most common general anaesthetics used during surgical procedures, including tumour resection. However, the effects of isoflurane on the viability and migration capacity of cancer cells, specifically in the context of ...
Mingxin Zhu +9 more
semanticscholar +1 more source
Effects of huperzine A on hippocampal inflammatory response and neurotrophic factors in aged rats after anesthesia [PDF]
Acta Cirúrgica Brasileira, 2020 Purpose To investigate the effects of huperzine A (HupA) on hippocampal inflammatory response and neurotrophic factors in aged rats after anesthesia.
Yi Cai, Penghan Huang, Yizu Xie
doaj +2 more sources
General anesthesia does not have persistent effects on attention in rodents [PDF]
, 2019 Background: Studies in animals have shown that general anesthesia can cause persistent spatial memory impairment, but the influence of anesthetics on other cognitive functions is unclear.
Amanda G. Nelson +8 more
core +2 more sources
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
Advanced Biology, EarlyView.RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang +13 more
wiley +1 more source
Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. [PDF]
PLoS ONE, 2012 Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory.
Diansan Su +6 more
doaj +1 more source
Inhalation anesthesia with isoflurane in a black jaguar (Panthera onca) for surgical repair of a fractured mandible [PDF]
, 2007 A black jaguar (Panthera onca) was anesthetized with a combination of medetomidine, ketamine and isoflurane in oxygen for radiological examination and surgical repair of a fractured mandible.
Bosmans, Tim +4 more
core
Neuroprotection provided by isoflurane pre-conditioning and post-conditioning
Medical Gas Research, 2017 Isoflurane, a volatile and inhalational anesthetic, has been extensively used in perioperative period for several decades. A large amount of experimental studies have indicated that isoflurane exhibits neuroprotective properties when it is administrated ...
Ming Jiang +6 more
semanticscholar +1 more source
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht +5 more
wiley +1 more source
Isoflurane Modulates Cardiac Mitochondrial Bioenergetics by Selectively Attenuating Respiratory Complexes [PDF]
, 2014 Mitochondrial dysfunction contributes to cardiac ischemia–reperfusion (IR) injury but volatile anesthetics (VA) may alter mitochondrial function to trigger cardioprotection.
Agarwal, Bhawana +4 more
core +2 more sources