Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiport power electronics circuitry for integration of renewable energy sources in low power applications : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Electrical Engineering at Massey University, Palmerston North, New Zealand [PDF]
, 2017 The increasing demand for electricity and the global concern about environment has led energy planners and developers to explore and develop clean energy sources.
Rehman, Zubair
core
Alone Self-Excited Induction Generators [PDF]
, 2016 In recent years, some converter structures and analyzing methods for the voltage regulation of stand-alone self-excited induction generators (SEIGs) have been introduced.
Doser, TL, Kesler, S
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Magnetically Integrated Multiport Converter for Energy Management in DC-Powered Buildings
Eletrônica de PotênciaMultiport converters have gained attention in the last few years as a key component for dc-powered buildings, more electric aircraft, and maritime applications.
Edivan Laercio Carvalho +4 more
doaj +1 more source
DC fault isolation study of bidirectional dual active bridge DC/DC converter for DC transmission grid application [PDF]
, 2015 Fast isolation and detection of DC faults is currently a limiting factor in high power DC transmission grid development. Recent research has shown that the role of DC/DC converters is becoming increasingly important in solving various DC grid challenges ...
Aboushady, Ahmed A. +2 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Realization of a 10 kW MES power to methane plant based on unified AC/DC converter [PDF]
, 2018 This paper presents a galvanic isolated multi output AC/DC topology that is suitable for Microbial electrosynthesis (MES) based Power to Methane energy storage systems.
Bosch, Pau +4 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source