Results 81 to 90 of about 53,308 (359)

Experimental investigation of the mooring system of a wave energy converter in operating and extreme wave conditions [PDF]

open access: yes, 2020
A proper design of the mooring systems for Wave Energy Converters (WECs) requires an accurate investigation of both operating and extreme wave conditions.
Begovic E.   +7 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Thermionic photovoltaic energy converter [PDF]

open access: yes, 1985
A thermionic photovoltaic energy conversion device comprises a thermionic diode mounted within a hollow tubular photovoltaic converter. The thermionic diode maintains a cesium discharge for producing excited atoms that emit line radiation in the ...
Chubb, D. L.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Nonlinear Analysis and Control of Interleaved Boost Converter Using Real-Time Cycle to Cycle Variable Slope Compensation [PDF]

open access: yes, 2017
Switched-mode power converters are inherently nonlinear and piecewise smooth systems that may exhibit a series of undesirable operations that can greatly reduce the converter's efficiency and lifetime.
Giaouris, Damian   +3 more
core   +2 more sources

Galvanically Isolated Modular Converter

open access: yes, 2018
The ever increasing penetration of renewable energy systems in the distribution grids will inevitably require profound changes in the grid infrastructure. One emerging direction, the medium voltage dc (MVdc) grids, is the cornerstone of this work. They are foreseen for offshore wind parks and onshore large scale renewables collection grids, future on ...
openaire   +1 more source

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